Evidence map›Paper›PMID 41392919›Full record

ArticleEmerging microbes & infections2026

Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses from humans in the United States, October 2024 to February 2025.

Philippe Noriel Q Pascua, Anton P Chesnokov, Ha T Nguyen, Chloe Champion, Rongyuan Gao, Juan A De La Cruz, Yunho Jang, Yasuko Hatta, Zhu Guo, Timothy M Uyeki and 4 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Philippe Noriel Q PascuaInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Anton P ChesnokovInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Ha T NguyenInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Chloe ChampionInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Rongyuan GaoInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Juan A De La CruzInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Yunho JangInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Yasuko HattaInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Zhu GuoInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Timothy M UyekiInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Han DiInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
James StevensInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Charles T DavisInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Larisa V GubarevaInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since October 2024, 55 human cases of influenza A(H5N1), clade 2.3.4.4b, were reported in the US. Sequencing of 46 viruses identified genotypes B3.13, D1.1, and D1.3. Virus genomes were analyzed for mutations associated with reduced antiviral susceptibility. Except for two, viruses from human cases were assessed as susceptible to antivirals and confirmed by

Indexed as

Antiviral AgentsInfluenza A Virus, H5N1 SubtypeInfluenza, HumanAnimalsDibenzothiepinsDogsDrug Resistance, ViralFemaleGenotypeHumansMiceMorpholinesMutationNeuraminidaseOrthomyxoviridae InfectionsPyridonesAntiviral AgentsbaloxavirDibenzothiepinsMorpholinesNeuraminidasePyridonesTriazinesA(H5N1) virusesbaloxavirbovine fludrug resistanceneuraminidaseneuraminidase inhibitors

Identifiers

PMID41392919
PMCPMC12777753

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.