Evidence map›Paper›PMID 41392319›Full record

ArticleScientific reports2025

Anatomical and anthropometric predictors of femoral and saphenous nerve location for ultrasound guided procedures.

Sara Mogedano-Cruz, Ignacio Benítez-Chulia, Laura González-Fernández, Ángel González-de-la-Flor, Juan Antonio Valera-Calero, Gustavo Plaza-Manzano, Gonzalo Jaén-Crespo, Carlos Romero-Morales

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Sara Mogedano-CruzFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
Ignacio Benítez-ChuliaFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
Laura González-FernándezFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
Ángel González-de-la-FlorFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
Juan Antonio Valera-CaleroDepartment of Physical Therapy, Faculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Gustavo Plaza-ManzanoDepartment of Physical Therapy, Faculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Gonzalo Jaén-CrespoFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
Carlos Romero-MoralesFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain. carlos.romero@universidadeuropea.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accurate identification of peripheral nerves using ultrasound is essential for the safe and effective application of image-guided interventions in pain management. The femoral nerve (FN) and saphenous nerve (SN) are common targets for peripheral nerve invasive techniques, yet their depth and anatomical variability can impact procedural success. The objective was to describe the ultrasound anatomy of the FN and SN in healthy individuals and analyze how anthropometric variables predict its location.

designA cross-sectional study was conducted in 30 healthy participants. Ultrasound measurements included subcutaneous tissue thickness, nerve depth, and cross-sectional area of the FN and SN. Anthropometric data such as BMI, limb length, and circumference measurements were also recorded. Pearson correlations and hierarchical regression models were used to identify predictors of nerve location.

resultsNo significant side-to-side differences were found for any variable (p > 0.05). Subcutaneous tissue thickness and limb circumference showed strong correlations with nerve depth. The final hierarchical regression model explained 67.0% of the variance in skin-to-FN distance and 82.3% for skin-to-SN distance. Subcutaneous tissue at the inguinal region and mid-thigh, as well as lower limb length and mid-thigh circumference, were significant predictors for FN depth. For the SN, subcutaneous thickness at mid-thigh, mid-thigh circumference, and inguinal subcutaneous tissue were the most relevant predictors.

conclusionAnthropometric variables, especially subcutaneous tissue thickness and limb circumferences, are reliable predictors of FN and SN depth in healthy subjects. These findings support the use of simple anatomical measures to improve planning and safety in ultrasound-guided procedures.

Indexed as

Femoral NerveUltrasonography, InterventionalAdultAnthropometryCross-Sectional StudiesFemaleHealthy VolunteersHumansMaleMiddle AgedUltrasonographyYoung AdultDiagnostic accuracy studiesFemoral nerveReliabilitySaphenous nerveUltrasonography

Identifiers

PMID41392319
PMCPMC12804967

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.