Evidence map›Paper›PMID 41392237›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2025

First evidence of photoinactivation of rapidly growing mycobacteria by tetra-cationic porphyrins with peripheral cisplatin.

Thaíse D Fussinger, Paulo R de Souza, Bernardo A Iglesias, Marli M A de Campos

Abstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thaíse D FussingerLaboratório de Micobacteriologia, Universidade Federal de Santa Maria, Campus Camobi, Santa Maria, 97105-900, RS, Brazil.
Paulo R de SouzaDepartamento de Física, Universidade Federal de Santa Maria, Campus Camobi, Santa Maria, 97105-900, RS, Brazil.
Bernardo A IglesiasLaboratório de Bioinorgânica e Materiais Porfirínicos, Universidade Federal de Santa Maria, Campus Camobi, Santa Maria, 97105-900, RS, Brazil. bernardopgq@gmail.com.ORCID http://orcid.org/0000-0002-4039-6316
Marli M A de CamposLaboratório de Micobacteriologia, Universidade Federal de Santa Maria, Campus Camobi, Santa Maria, 97105-900, RS, Brazil.

Funding

CAPES Finance Code 001CNPq CNPqFAPERGS FAPERGS
6 · The paper itself

Abstract

This manuscript describes the evaluation of the photoinactivation of cationic meso-tetra(pyridyl)porphyrins combined with cisplatin as photosensitizers (PS) for the photodynamic inactivation of Rapidly Growing Mycobacteria (RGM) strains. Two porphyrin derivatives, 3-cis-PtTPyP and 4-cis-PtTPyP, were synthesized according to methodologies previously described in the literature. The Antimicrobial Photodynamic Therapy (aPDT) experiments were conducted on different RGM strains, including Mycobacteroides abscessus subsp. abscessus (ATCC 19977), Mycolicibacterium fortuitum (ATCC 6841), Mycobacteroides abscessus subsp. massiliense (ATCC 48898), and Mycolicibacterium smegmatis (ATCC 700084), using appropriate concentrations of PS under conditions of exposure to a white-light source for 90 min (irradiance of 50 mW cm

Indexed as

Anti-Bacterial AgentsCisplatinMycobacteriumPhotosensitizing AgentsPorphyrinsLightMicrobial Sensitivity TestsMicrobial ViabilityPhotochemotherapyAnti-Bacterial AgentsCisplatinPhotosensitizing AgentsPorphyrinsCisplatin-porphyrinsMycobacteriaPhotobiologyPhotodynamic inactivationPorphyrins

Identifiers

PMID41392237
PMCPMC12702834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.