Evidence map›Paper›PMID 41392213›Full record

ArticleCardiovascular and interventional radiology2026

Feasibility and Safety of Percutaneous Gallbladder Cryoablation with and Without Gallstone Extraction for Calculous and Acalculous Cholecystitis.

Jacob Abraham, Michelle Mai, Abdifatah Omar, Jessica H Yoon, Hyeonseon Kim, Aaron Wp Maxwell, Timothy Murtha, Steve Kwon, Daehee Kim

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Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacob AbrahamThe Warren Alpert Medical School of Brown University, Providence, RI, 02903, USA.
Michelle MaiThe Warren Alpert Medical School of Brown University, Providence, RI, 02903, USA.
Abdifatah OmarThe Warren Alpert Medical School of Brown University, Providence, RI, 02903, USA.
Jessica H YoonDepartment of Radiology, Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, 02903, USA.
Hyeonseon KimDepartment of Radiology, Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, 02903, USA.
Aaron Wp MaxwellDepartment of Radiology, Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, 02903, USA.
Timothy MurthaDepartment of Surgery, Warren Alpert Medical School of Brown University, Providence, RI, 02903, USA.
Steve KwonDepartment of Surgery, Boston University School of Medicine, Roger Williams Medical Center, Providence, RI, 02908, USA.
Daehee KimDepartment of Radiology, Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, 02903, USA. daehee_kim@brown.edu.ORCID http://orcid.org/0000-0002-6974-3529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the feasibility and safety of percutaneous gallbladder cryoablation combined with gallstone extraction for calculous cholecystitis and cryoablation alone for acalculous cholecystitis. MATERIALS AND

methodsA dual-tertiary center retrospective case series included 12 patients (median age, 66.0 years; three females and nine males) with benign gallbladder disease who underwent percutaneous gallbladder cryoablation between April 2023 and May 2025. Ten patients underwent percutaneous cholangioscopy-guided gallstone extraction prior to cryoablation, while two patients without gallstones received cryoablation alone. Descriptive statistics were collected for patient demographics, clinical presentation, procedural details, technical success, adverse events, symptom recurrence and resolution rates, and imaging findings.

resultsThe median follow-up was 540.5 days. Technical success was achieved in 91.7% (11/12), with one procedure aborted due to the inability to safely hydrodissect the colon from the gallbladder. All 11 patients who underwent successful cryoablation reported complete symptom resolution at 1-month and during subsequent follow-up. Follow-up imaging demonstrated progressive involution of the devitalized, nonenhancing gallbladder. No immediate procedure-related complications occurred, and all patients were discharged within 24 h. One patient developed a minor procedure-related adverse event on post-procedure day 4 (self-limited scrotal edema), and another experienced transient biliary obstruction 3 months later, presumably related to the choledochocele.

conclusionsGallbladder cryoablation, performed alone for acalculous cholecystitis or in combination with gallstone extraction for calculous cholecystitis, is technically feasible, safe, and associated with effective symptom relief.

Indexed as

Acalculous CholecystitisCryosurgeryGallstonesAgedAged, 80 and overFeasibility StudiesFemaleGallbladderHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeCholecystitisCryoablationGallbladderGallstone extraction

Identifiers

PMID41392213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.