Evidence map›Paper›PMID 41392157›Full record

ArticleScientific reports2025

Design of isolated lithographic SERS structures with enhanced sensitivity.

Xin Jin, Hui Xia, S R J Brueck

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xin JinArmonica Technologies, Inc, 5901 Indian School Road, Albuquerque, NM, 87110, USA.
Hui XiaArmonica Technologies, Inc, 5901 Indian School Road, Albuquerque, NM, 87110, USA.
S R J BrueckArmonica Technologies, Inc, 5901 Indian School Road, Albuquerque, NM, 87110, USA. steven.brueck@armonicatech.com.

Funding

Single molecule DNA/RNA sequencing technology based on a parallel Raman scattering readout in a coupled nanochannel/nanopore systemR44HG011608 · NHGRI · ARMONICA TECHNOLOGIES, INC. · PI BRUECK, STEVEN · 2022 to 2023
$1.9M
NHGRI NIH HHS R44 HG011608NIH HHS 5R44HG011608
6 · The paper itself

Abstract

Surface-enhanced Raman scattering (SERS) on lithographically fabricated structures has been extensively explored. The consensus is that non-resonant single-molecule sensitivity (SMSERS) is not achievable with isolated structures. Difficult to manufacture closely spaced pairs of structures, akin to the closely approaching (< 1 nm separation) spheres identified in colloidal clusters, are thought to be required. This scale is beyond the capability of current lithographic approaches. FDTD modeling is used to explore improvements in the electric field enhancement for isolated lithographic structures. Electric field enhancement factors (β=E

Identifiers

PMID41392157
PMCPMC12886810

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.