Evidence map›Paper›PMID 41391881›Full record

ArticleJournal of biophotonics2025

Probing polarization response of monolayer cell cultures with entangled photon pairs.

L Zhang, V R Besaga, P Rühl, C Zou, S H Heinemann, Y Wang, F Setzpfandt

Abstract read
In one paragraph

Article in Journal of biophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Application of quantum imaging in biology.Biomedical optics express · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L ZhangInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, China.ORCID 0009-0003-6465-7490
V R BesagaInstitute of Applied Physics, Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-4722-2511
P RühlCenter for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-3554-3107
C ZouInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-4275-1630
S H HeinemannCenter for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-4144-0251
Y WangInstitute of Microelectronics of the Chinese Academy of Sciences, Beijing, China.
F SetzpfandtInstitute of Applied Physics, Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-7919-8181

Funding

China Scholarship Council 201904910805Cluster of Excellence "Balance of the Microverse" 390713860European Union's Horizon 2020 research and innovation programme 899580Federal Ministry of Education and Research 13 N16441Federal Ministry of Education and Research FKZ 13 N14877ProChance-career program of the Friedrich Schiller University Jena AZ 2.11.3-A1/2022-01
6 · The paper itself

Abstract

This study addresses the critical need for high signal-to-noise ratio in optical detection methods for biological sample discrimination under low-photon-flux conditions to ensure accuracy without compromising sample integrity. We explore polarization-based probing, which often excels over intensity modulation when assessing a specimen's morphology. Leveraging non-classical light sources, our approach capitalizes on sub-Poissonian photon statistics and quantum correlation-based measurements. We present a novel, highly sensitive method for probing single-layer cell cultures using entangled photon pairs. Our approach demonstrates potential for monolayer cell analysis, distinguishing between two types of monolayer cells and their host medium. The experimental results highlight our method's sensitivity, showcasing its potential for biological sample detection using quantum techniques, and paving the way for advanced diagnostic methodologies.

Indexed as

Cell Culture TechniquesPhotonsHumansSignal-To-Noise Ratioentangled photon pairsmonolayer cell culturespolarization projective measurementsquantum polarization state tomography

Identifiers

PMID41391881
PMCPMC12702643

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.