Evidence map›Paper›PMID 41391542›Full record

ArticleThe Journal of pediatrics2026

Application of the Target Trial Emulation Framework to Studies in the Pediatric Population.

Jenny W Sun, Daniel B Horton, Timothy J Savage, Mehmet Burcu, Sonia Hernandez-Diaz

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jenny W SunWorldwide Medical and Safety, Pfizer Inc, New York, NY; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ. Electronic address: Jenny.Sun@pfizer.com.
Daniel B HortonRutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ; Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ.
Timothy J SavageDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA; Department of Medicine, Harvard Medical School, Boston, MA; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA.
Mehmet BurcuDepartment of Epidemiology, Merck & Co, Inc, Rahway, NJ.
Sonia Hernandez-DiazDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

Funding

New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
NJ ACTS: A Platform for Translational Science in New JerseyUM1TR004789 · NCATS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Reynold Alexander Panettieri · 2024 to 2026
$16.8M
RESEARCH TRAINING IN PEDIATRIC EMERGENCY MEDICINET32HD040128 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI Kenneth D. Mandl · 2001 to 2026
$5.0M
Impact of obesity treatments on subsequent pregnancy outcomesR01HD097778 · NICHD · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sonia Hernandez-Diaz · 2019 to 2026
$4.2M
Safety of Drugs Commonly Used Off-Label in Children Despite Insufficient Evidence of Efficacy and SafetyR01HD109335 · NICHD · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Daniel Benjamin Horton · 2022 to 2026
$3.3M
The development of a systematic approach to harness real-world evidence for the evaluation of medication safety and effectiveness in childrenK08HD110600 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI Timothy John Savage · 2023 to 2026
$671k
NCATS NIH HHS UL1 TR003017NCATS NIH HHS UM1 TR004789NICHD NIH HHS K08 HD110600NICHD NIH HHS R01 HD097778NICHD NIH HHS R01 HD109335NICHD NIH HHS T32 HD040128
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epidemiologyobservational studiestarget trial

Identifiers

PMID41391542
PMCPMC13093582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.