Evidence map›Paper›PMID 41391501›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2026

Holo-Stroke-ii: Stroke care through stroke hologram teleportation- inpatient immersion.

Weichen Liu, Ben Shifflett, Teri McQuaid, Marissa D'Souza, Reza Bavarsad Shahripour, Kunal Agrawal, Dawn M Meyer, Derek Dutt, Dale Keehan, Nadir Weibel and 1 more

Abstract readComparative Study
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Weichen LiuUCSD Department of Mathematics, University of California San Diego. Electronic address: wel008@ucsd.edu.
Ben ShifflettUCSD Neurosciences. Electronic address: bshiffle@health.ucsd.edu.
Teri McQuaidUCSD Neurosciences. Electronic address: tmcquaid@health.ucsd.edu.
Marissa D'SouzaUCSD Neurosciences. Electronic address: madsouza@health.ucsd.edu.
Reza Bavarsad ShahripourUCSD Neurosciences. Electronic address: rbavarsadshahripour@health.ucsd.edu.
Kunal AgrawalUCSD Neurosciences. Electronic address: kuagrawal@health.ucsd.edu.
Dawn M MeyerUCSD Neurosciences. Electronic address: dmmeyer@health.ucsd.edu.
Derek DuttUCSD Information Services. Electronic address: ddutt@health.ucsd.edu.
Dale KeehanUCSD Information Services. Electronic address: dkeehan@health.ucsd.edu.
Nadir WeibelUCSD Computer Science and Engineering & Design Lab UC San Diego. Electronic address: weibel@ucsd.edu.
Brett C MeyerUCSD Neurosciences. Electronic address: bcmeyer@health.ucsd.edu.

Funding

San Diego StrokeNet Regional Coordinating CenterU24NS107225 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRETT C MEYER · 2018 to 2026
$2.4M
NINDS NIH HHS U24 NS107225
6 · The paper itself

Abstract

backgroundTelestroke allows care irrespective of distance but has limitations in degree of immersive interaction. Augmented Reality (AR) holds promise, enabling providers and patients to interact as if in the same physical space. Prior investigations have shown immersive satisfaction for Holo-Stroke allowing 3D hologram providers to be transmitted to distant sites, and allowing for hologram assessments of Large Vessel Occlusions (LVOs).

methodsWe presented 2 evaluation techniques (both telestroke and Holo-Stroke) to a group of stroke service inpatients. Three optical cameras with depth sensing capability were placed around the stroke provider, with imaging streams transmitted in real-time via intranet to a HoloLens 2 Head-Mounted-Display (HMD) worn by patient at a distant site. The provider was visualized in the patient's room as a hologram. Sample MRI, CTA, NIHSS picture card, and animation video were also visible to the patient through the HMD. Satisfaction questions were assessed via Likert scale. Wilcoxon Signed Rank, and Exact Binomial Test were used.

resultsTwenty inpatients with deficits consistent with acute stroke participated. Median age was 68 years, 45 % were female, 55 % white, and 20 % Hispanic. Median Likert scores favored Holo-Stroke over telestroke overall (47(93 %) vs 25.5(48 %);p < 0.001), and for immersion (10(92 %) vs 4(37 %);p < 0.001), beneficial technique (10(95 %) vs 5.5(55 %);p < 0.001), and seeing images (10(97 %) vs 5(45 %);p < 0.001). Clinical observations were overwhelmingly favorable. DISCUSSION: This Holo-Stroke telestroke, assessing acute stroke patients in the inpatient setting using wireless 3D hologram technique, resulted in robust immersion and significant increase in patient satisfaction. Although future evaluations of Holo-Stroke in acute telestroke are still warranted, Holo-Stroke has now clearly been shown to improve inpatient immersion and satisfaction.

Indexed as

Augmented RealityHolographyInpatientsStrokeTelemedicineAgedAged, 80 and overFemaleHumansMaleMiddle AgedPatient SatisfactionPredictive Value of TestsAugmented RealityHologramImmersionInpatientSatisfactionTelemedicineTelestroke

Identifiers

PMID41391501
PMCPMC13472508

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.