Evidence map›Paper›PMID 41391483›Full record

ArticleJournal of the National Cancer Institute2026

Childhood cancer survival in Africa, Asia, Latin America and the Caribbean, during 2008-2017 (SURVCAN-3): a population-based benchmarking study of 16 821 children.

Dagrun Slettebø Daltveit, Eileen Morgan, Aude Bardot, Eva Steliarova-Foucher, Amanuel Damie, Marc Hagenimana, Nisrine Khoubila, Florencia Moreno, Isabelle Soerjomataram

Abstract read
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Article in Journal of the National Cancer Institute, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Dagrun Slettebø DaltveitCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-0903-1140
Eileen MorganCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-4242-6240
Aude BardotCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-8784-5051
Eva Steliarova-FoucherCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-5777-9199
Amanuel DamieDepartment of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-8512-0540
Marc HagenimanaRwanda Biomedical Centre, Kigali, Rwanda.
Nisrine KhoubilaDepartment of Hematology and Pediatric Oncology, Faculty of Medicine and Pharmacy, Hospital 20 August 1953, CHU Ibn Rochd, Hassan II University, Casablanca, Morocco.ORCID 0000-0001-5362-0412
Florencia MorenoInstituto Nacional del Cancer, Buenos Aires, Argentina.ORCID 0000-0001-6181-5025
Isabelle SoerjomataramCancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-6017-741X

Funding

Global Health Working GroupGlobal Health Working Group at the Medical FacultyIARCMartin-Luther-University Halle-WittenbergTata Memorial Hospital DCA/CSU/2016/02The University of BergenWorld Health Organization 001
6 · The paper itself

Abstract

backgroundAccurate information on childhood cancer survival is essential for improving health systems. Survival is believed to be low in low-resource countries, but population-based survival estimates are scant. We aim to provide reliable and comparable survival estimates in these settings.

methodsWe included 16 821 patients from 47 population-based cancer registries in 23 countries in Africa, Latin America and the Caribbean, and Asia. We used the Cancer Survival in Countries in Transition project data (children aged younger than 15 years, diagnosed 2008-2012, followed until 2014) and data from Rwanda (2013-2017, followed until 2022). We estimated 1-year, 3-year, and 5-year observed survival using the Kaplan-Meier method, by diagnostic group, country, region, Human Development Index, income, and sex.

resultsSurvival was higher in registries included from the Caribbean (namely, Puerto Rico [United States], Martinique [France]) and Central America (Costa Rica), Asia, and the Middle East and North Africa compared with those included from South America and sub-Saharan Africa. Survival correlated with the Human Development Index. For leukemia, 3-year survival varied from 30.4% (95% confidence interval [CI] = 12.4% to 50.6%) in Kenya to 89.5% (95% CI = 83.8% to 93.2%) in Puerto Rico; for central nervous system tumors from 32.0% (95% CI = 13.9% to 51.8%) in Algeria to 79.3% (95% CI = 69.1% to 86.5%) in Puerto Rico. The findings should be interpreted with care, as registry coverage varies and may not reflect national and regional survival.

conclusionThe variability of the population-based survival estimates across predominantly low- and middle-income countries highlights gaps in cancer registration, access to care, and quality of care. This study provides benchmark data for the World Health Organization Global Initiative for Childhood Cancer generated by population-based cancer registries, which should be supported in all countries.

Indexed as

BenchmarkingNeoplasmsAdolescentAfricaAsiaCaribbean RegionChildChild, PreschoolDeveloping CountriesFemaleHumansInfantInfant, NewbornLatin AmericaMaleRegistries

Identifiers

PMID41391483
PMCPMC13339078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.