Evidence map›Paper›PMID 41391109›Full record

Trial reportSchizophrenia bulletin2026

Enhancing Assertive Community Treatment With Cognitive Behavioral Social Skills Training for Schizophrenia: II. Ecological Momentary Assessment Outcomes in a Pragmatic Randomized-Controlled Trial.

Matthias Pillny, Kim T Mueser, Jason Holden, Gregory A Aarons, David Sommerfeld, Dimitri Perivoliotis, Eric Granholm

Registry-linked trialAbstract readPragmatic Clinical Trial
In one paragraph

Trial report in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02254733 (Enhancing Assertive Community Treatment With Cognitive Behavioral Therapy and Social Skills Training for Schizophrenia.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02254733 nacompletednot on this map

Enhancing Assertive Community Treatment With Cognitive Behavioral Therapy and Social Skills Training for Schizophrenia.

TypeinterventionalSponsorVeterans Medical Research FoundationRan2012 to 2016Enrolled178ConditionsSchizophreniaArmsCognitive Behavioral Social Skills Training (CBSST), Assertive Community Treatment (ACT)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthias PillnyClinical Psychology and Psychotherapy, Institute of Psychology, Faculty of Psychology and Human Movement Science, Universität Hamburg, Hamburg 20146, Germany.ORCID 0000-0003-2395-8433
Kim T MueserCenter for Psychiatric Rehabilitation, Boston University, Boston MA 02215, United States.ORCID 0000-0002-1482-8314
Jason HoldenDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States.
Gregory A AaronsDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States.
David SommerfeldDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States.
Dimitri PerivoliotisDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States.ORCID 0000-0003-4254-0155
Eric GranholmDepartment of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States.ORCID 0000-0003-2040-7951

Funding

Enhancing Assertive Community Treatment with CBT and SST for SchizophreniaR01MH091057 · NIMH · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GRANHOLM, ERIC L · 2011 to 2015
$3.1M
Federal Ministry of Education and Research Germany (BMBF)Free and Hanseatic City of Hamburg UHH/VP3/4/425 IRF_2022_PillnyNIMH NIH HHS R01 MH091057
6 · The paper itself

Abstract

background and hypothesisIndividuals with schizophrenia experience severe impairments in everyday functioning. Cognitive behavioral social skills training (CBSST) has demonstrated moderate effects on functional outcomes in controlled trials. This study examined whether CBSST, when integrated into assertive community treatment (ACT), improves daily-life functioning as assessed by ecological momentary assessment (EMA). STUDY

designThis was a secondary analysis of a pragmatic randomized controlled trial involving 155 participants diagnosed with schizophrenia or schizoaffective disorder. Participants were randomized to receive either ACT + CBSST (n = 75) or ACT alone (n = 80). Assessments occurred at baseline, 9 months (n = 100), and 18 months (n = 67) to capture real-time reports of "productive" and "non-productive" activities. The primary outcome was productive activity. Secondary outcomes included non-productive activity, the productive/non-productive activity ratio, anhedonia, and defeatist beliefs. Linear mixed models were used to test for differential changes over time between groups. STUDY

resultsAlthough the groups differed at baseline, the ACT + CBSST group showed significantly greater improvements over time relative to the ACT group in productive activities, the productive/non-productive activity ratio, and in reductions in anhedonia and defeatist beliefs. However, between-group differences at follow-up were not statistically significant.

conclusionsAdding CBSST to ACT may yield greater improvements in daily-life functioning than ACT alone. While these results support the potential added value of integrating CBSST into routine care, further research is needed to confirm its superiority. Together with the companion report from this study, these findings suggest that EMA may offer a sensitive approach for detecting changes in real-world functioning in clinical trials.Trial Registration: ClinicalTrials.gov (NCT02254733; https://clinicaltrials.gov/).

Indexed as

Activities of Daily LivingCognitive Behavioral TherapyCommunity Mental Health ServicesEcological Momentary AssessmentOutcome Assessment, Health CarePsychotic DisordersSchizophreniaSocial SkillsAdultFemaleFollow-Up StudiesHumansMaleMiddle Agedassertive community treatmentcognitive behavior therapyEMAESMfunctioningschizophreniasocial skills

Identifiers

PMID41391109
PMCPMC12809843

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.