Evidence map›Paper›PMID 41390859›Full record

ArticleScientific reports2025

Choosing dialysis modality in patients aged 75 and above with end-stage kidney disease: a multicenter cohort study.

Yaohua Hu, Xueyan Zhu, Yingying Liu, Liming Yang, Zhanshan Sun, Xiaoxuan Zhang, Jian Li, Xinyang Li, Xinyu Gao, Mengyuan Yu and 1 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yaohua HuDepartment of Nephrology, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, 130041, Jilin Province, China.
Xueyan ZhuDepartment of Nephrology, Jilin Central Hospital, Jilin, 132011, Jilin Province, China.
Yingying LiuDepartment of Nephrology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Liming YangDepartment of Nephrology, The First Hospital of Jilin University-the Eastern Division, Changchun, 130041, Jilin Province, China.
Zhanshan SunDepartment of Nephrology, Xing'anmeng People's Hospital, Ulan Hot, 137400, Inner Mongolia Autonomous Region China, China.
Xiaoxuan ZhangDepartment of Nephrology, Jilin FAW General Hospital, Changchun, 130041, Jilin Province, China.
Jian LiDepartment of Nephrology, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, 130041, Jilin Province, China.
Xinyang LiDepartment of Nephrology, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, 130041, Jilin Province, China.
Xinyu GaoDepartment of Nephrology, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, 130041, Jilin Province, China.
Mengyuan YuDepartment of Nephrology, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, 130041, Jilin Province, China.
Wenpeng CuiDepartment of Nephrology, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, 130041, Jilin Province, China. wenpengcui@163.com.

Funding

Jilin Province Medical and Health Talent Special Project 2024WSZX-B01
6 · The paper itself

Abstract

End-stage kidney disease (ESKD) is a growing health issue, especially among the very elderly. The optimal dialysis method for very elderly patients with ESKD remains uncertain, and there is a lack of evidence regarding the survival benefits of hemodialysis (HD) versus peritoneal dialysis (PD). This study is a multicenter cohort investigation that included 234 very elderly patients aged 75 years and older with ESKD who received HD or PD across six hospitals in China from January 2013 to December 2020. We employed Propensity Score Matching (PSM) to minimize the influence of confounding factors. Survival analyses were conducted using Kaplan-Meier curves, log-rank tests, and multivariable Cox proportional hazards regression models for the matched cohorts. In the multicenter cohort study with 234 very elderly ESKD patients, PSM was employed, with each group consisting of 56 participants, averaging 79.76 ± 4.15 years in age and having a male composition of 47.44%. Kaplan-Meier survival analysis indicated with no significant difference in survival rates (log-rank p = 0.123). Further analysis, excluding participants with less than 3 months of survival, also showed no significant differences. Cox regression with multiple variables indicated a HR of 0.73 (95% CI: 0.49, 1.10) for HD versus PD, with a p-value of 0.132. This investigation did not demonstrate a statistically significant difference in survival between PD and HD among very elderly patients with ESKD.

Indexed as

Kidney Failure, ChronicPeritoneal DialysisRenal DialysisAgedAged, 80 and overChinaCohort StudiesFemaleHumansKaplan-Meier EstimateMalePropensity ScoreProportional Hazards ModelsSurvival RateEnd-stage kidney diseaseHemodialysisOctogenarian patientsPeritoneal dialysis

Identifiers

PMID41390859
PMCPMC12808230

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