ArticleBMC veterinary research2025
Physiological effects of a pre-anesthetic single dose of gabapentin on Xylazine/Ketamine anesthesia in rabbits.
Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs common pets, rabbits are frequently brought to veterinarians for examination and medical care. Many diagnostic and surgical treatments require anesthesia, which is linked to a higher perioperative risk in rabbits than in dogs and cats.
objectiveTo assess the impact of a single 25 mg/kg oral dose of gabapentin on the depth and duration of anesthesia and hemodynamic stability of different anesthetic regimes.
methodsTwenty adult healthy New Zealand male rabbits weighing 2.5 ± 0.5 kg were used in this study randomly and equally divided using a computer-generated random number table into four groups: group A (gabapentin/xylazine/ketamine), group B (gabapentin/ketamine), group C (xylazine/ketamine), and group D (ketamine only). All experimental groups were evaluated through assessment of anesthetic depth, vital, hematological, and serum biochemical parameters.
resultsOur data revealed the enhanced reflex suppression and prolonged recovery observed in the anesthetic regime of group (A) with short induction time and prolonged recovery with remarkable muscle relaxation. LIMITATIONS: The study was limited by a small sample size (n = 20), which may reduce the statistical power and generalizability of the findings. Additionally, postoperative pain assessment using validated scoring tools was not performed, and the results should be interpreted with caution regarding long-term analgesic efficacy.
conclusionA single oral dose of gabapentin minimizes the ketamine's catalepsy, reducing its induction time, delaying and improving the recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.