ArticleDiabetology & metabolic syndrome2025
Effect of body shape index trajectories on kidney disease incidence and subsequent death in individuals with type 2 diabetes.
Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThis study aimed to identify three-year trajectories of body mass index (BMI), a body shape index (ABSI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), and body roundness index (BRI); to assess their association with incident chronic kidney disease (CKD) and mortality; and to investigate potential sex difference in these associations.
methodsThis retrospective longitudinal study included 8,445 patients with type 2 diabetes mellitus (T2DM) who were free of CKD at baseline, had ≥ 3 years of follow-up, and attended the Diabetes Care Management Program of a medical center in Taichung from 2001 to 2012 (with the follow-up period ending in 2021). Cluster analysis was performed to group three-year trajectory patterns, and Cox proportional hazard models were used to assess the associations.
resultsDuring a mean follow-up of 7.88 years, 2,901 (34.35%) participants developed CKD, and 856 (10.14%) died. An elevated risk of CKD incidence was associated with several trajectory clusters. Specifically, associations were found with: Cluster 1 (constant low-level) for ABSI, WC, WHtR, and BRI trajectories; Cluster 4 (high level with decreasing trend) for WC and BRI trajectories; and Cluster 5 (low level with increasing trend) for BMI, WC, WHtR, and BRI trajectories. Regarding mortality, an elevated risk was associated with: Cluster 1 (constant low-level) for WC and WHtR trajectories; Cluster 3 (constant high-level) for ABSI and BRI trajectories; and Cluster 5 (low level with increasing trend) for BMI trajectory.
conclusionLongitudinal trajectories of various body shape indices predict CKD incidence and mortality risk in T2DM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.