Evidence map›Paper›PMID 41390333›Full record

ArticleScientific reports2025

Utilization of psychotherapy, pharmacotherapy, and their combination by individuals with current or residual depression: results from five annual nationally representative German surveys.

Louisa Breuer, Andreas Czaplicki, Ulrich Hegerl, Hanna Reich

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Louisa BreuerDepression Research Centre of the German Depression Foundation, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt am Main, Germany. louisa.breuer@deutsche-depressionshilfe.de.ORCID 0009-0003-1484-8897
Andreas CzaplickiDepression Research Centre of the German Depression Foundation, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt am Main, Germany.ORCID 0000-0003-4652-6991
Ulrich HegerlDepression Research Centre of the German Depression Foundation, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt am Main, Germany.ORCID 0000-0002-3039-7470
Hanna ReichDepression Research Centre of the German Depression Foundation, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt am Main, Germany.ORCID 0000-0002-9577-1144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a common and burdensome mental disorder affecting more than 320 million people worldwide. Clinical practice guidelines recommend psychotherapy, antidepressant pharmacotherapy, or their combination as the cornerstones of evidence-based treatment. Despite these well-established therapeutic options, a substantial proportion of individuals with depression remain untreated. In Germany, available estimates of the current treatment gap are outdated. The present study therefore aims to examine report the utilization of psychotherapy, antidepressant pharmacotherapy, or their combination among adults in Germany who self-reported a diagnosis of depression. In addition, we explore potential differences in treatment utilization according to sociodemographic characteristics, specifically sex and age. Between 2018 and 2022, annual population-representative surveys were conducted in Germany. A total of N = 3,416 individuals who self-reported having been professionally diagnosed with depression at least once in their lifetime and who indicated current acute or residual symptoms were included in the present analysis. Overall, 63.4% of participants reported using at least one guideline-based treatment for their current depressive episode or residual symptoms. Specifically, 13.5% reported receiving psychotherapy, 26.5% pharmacotherapy, and 23.4% a combination of both. The likelihood of utilizing psychotherapy decreased with age (18-29 years: OR = 1.22, 95% CI = 0.91-1.64; 60-69 years: OR = 0.36, 95% CI = 0.24-0.52), whereas the likelihood of pharmacotherapy use increased with age (18-29 years: OR = 0.74, 95% CI = 0.54-1.01; 60-69 years: OR = 2.46, 95% CI = 1.89-3.23). Although self-reported utilization of guideline-based treatment for depression was higher than previously reported, depression in adulthood likely remains undertreated. These findings highlight the need to strengthen access to evidence-based interventions and to promote long-term treatment adherence and self-management strategies.

Indexed as

Antidepressive AgentsDepressionPsychotherapyAdolescentAdultAgedCombined Modality TherapyFemaleGermanyHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAntidepressive AgentsDepressionPharmacotherapyPsychotherapyRepresentative surveySelf-report

Identifiers

PMID41390333
PMCPMC12708866

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.