Observational studyInterdisciplinary cardiovascular and thoracic surgery2025
Stent and Resection Anastomosis in Patients with Complex Tracheal Stenosis: The Stars Retrospective Multicenter Trial.
Observational study in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Reinforcement of skin flap tracheal reconstruction with porous titanium nickelide implants: A novel approach to persistent tracheal defect closure.JTCVS techniques · 2026Article
- Crico-tracheal resection and anastomosis for primary and secondary tumours of the laryngo-tracheal junction: a single centre series of 78 patients.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026Article
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Authors and funding
18 authors.
Funding
Abstract
objectivesComplex tracheal stenosis poses significant treatment challenges, especially in patients deemed inoperable due to anatomical or clinical factors. This study aimed to assess the outcomes of 2 primary interventions-tracheal resection-anastomosis and tracheal stenting-in an observational, international, retrospective cohort.
methodsMulticenter study conducted on adult patients with benign complex tracheal stenosis who underwent either tracheal resection or silicone stent placement between 2009 and 2023, and who had at least 24 months of follow-up after resection-anastomosis or 12 months of follow-up after stent removal. Complete clinical resolution, defined as the absence of symptoms and no need for reintervention 1 year after treatment, was the primary outcome. Secondary analyses assessed the impact of treatment modality and patient risk profile on outcomes.
resultsClinical resolution was achieved in 110 of 125 patients. Resection-anastomosis was associated with significantly higher hazard risk of resolution compared to stenting (adjusted HR = 2.0; 95% CI, 1.26-3.33; P = .003). In low-risk patients, surgery was notably superior (crude resolution HR = 3.01; 95% CI, 1.37-7.93, P = .004), while outcomes were not significantly different between the two treatments in high-risk patients with cardiorespiratory comorbidities or extended stenosis. Approximately 70% of patients treated with stenting remained symptom-free after 1 year.
conclusionsResection-anastomosis remains the preferred treatment for operable complex tracheal stenosis, offering the highest likelihood of long-term resolution. However, in high-risk or inoperable patients, endoscopic stenting provides a valuable alternative with acceptable outcomes. A tailored, multidisciplinary approach is essential to optimize treatment selection and avoid unnecessary tracheotomies.
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