Evidence map›Paper›PMID 41390012›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2026

Resurgence of visceral and cutaneous leishmaniasis in Kajiado County, Kenya: A coordinated response and entomological survey.

Damaris Matoke-Muhia, Barrack O Owino, Steve Kiplagat, Hannah N Mwangi, Johnstone M Ingonga, Daniel Njenga, Benny B Septer, Mwatela Kitondo, Daniel Mwiti, Charles Magiri and 10 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

20 authors.

Damaris Matoke-MuhiaCentre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.
Barrack O OwinoInternational Centre of Insect Physiology and Ecology, icipe, Nairobi, Kenya; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK.
Steve KiplagatInternational Centre of Insect Physiology and Ecology, icipe, Nairobi, Kenya.
Hannah N MwangiCentre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya; Kreavet, Kruibeke, Belgium.
Johnstone M IngongaCentre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.
Daniel NjengaCentre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.
Benny B SepterCentre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.
Mwatela KitondoAfrican Centre for Community Investments in Health (ACCIH), Nairobi, Kenya.
Daniel MwitiDivision of Vector-Borne and Neglected Tropical Diseases, Ministry of Health, Nairobi, Kenya.
Charles MagiriFoundation for Innovative New Diagnostics (FIND), Nairobi, Kenya.
Hellen NyakundiAfrican Centre for Community Investments in Health (ACCIH), Nairobi, Kenya.
Juliet OnditiInternational Centre of Insect Physiology and Ecology, icipe, Nairobi, Kenya.
Sarah WeihlNortheastern University, Boston, Massachusetts, USA.
Catherine WengerNortheastern University, Boston, Massachusetts, USA.
Abhay SatoskarDivision of Experimental Pathology, Ohio State University, Columbus, Ohio, USA.
Jandouwe VillingerInternational Centre of Insect Physiology and Ecology, icipe, Nairobi, Kenya.
Shaden KamhawiVector Molecular Biology Section, National Institute of Allergy and Infectious Diseases (NIAID), Rockville, Maryland, USA.
Joseph NdunguFoundation for Innovative New Diagnostics (FIND), Nairobi, Kenya.
Richard WamaiAfrican Centre for Community Investments in Health (ACCIH), Nairobi, Kenya; Northeastern University, Boston, Massachusetts, USA.
Daniel K MasigaInternational Centre of Insect Physiology and Ecology, icipe, Nairobi, Kenya. Electronic address: dmasiga@icipe.org.

Funding

Eneza Data Science: Enhancing Data Science Capability and Tools for Health in East AfricaUE5TW012539 · FIC · INTERNATIONAL CENTRE OF INSECT PHYSIOLOG · PI MASIGA, DANIEL KANANI · 2023 to 2025
$600k
FIC NIH HHS UE5 TW012539
6 · The paper itself

Abstract

objectivesThis study investigated emergence of visceral leishmaniasis (VL) in 2021, in Kajiado County in Kenya, representing a newly recognized region of endemic transmission.

methodsThe investigation involved community sensitization, medical camps, and entomological surveys across eight villages. We screened 100 individuals with indicative symptoms of leishmaniasis, and also carried out an entomological survey.

resultsWe found 10 patients of VL, predominantly in children under 15. Of 22 suspected cutaneous leishmaniasis (CL) cases, eight were confirmed with Leishmania tropica. Entomological surveys identified 4781 sandflies, with Sergentomyia species being most abundant. DNA of Leishmania donovani was detected in multiple Sergentomyia species and Phlebotomus saevus, while L. tropica DNA was found in P. saevus. Blood meal analysis revealed a strong preference for human blood, followed by goats, indicating high human-vector contact.

conclusionThe study highlights the value of a multisectoral approach to outbreak responses, which resulted establishment of two new treatment centers in Kajiado, enhancing continuing access to care and associated surveillance. The study confirmed L. donovani and L. tropica as the causative agents for VL and CL, respectively, in Kajiado. The unusual co-occurrence of both forms complicates treatment and raises concerns about potential genetic recombination.

Indexed as

Insect VectorsLeishmaniasis, CutaneousLeishmaniasis, VisceralAdolescentAdultAnimalsChildChild, PreschoolFemaleGoatsHumansInfantKenyaLeishmania donovaniLeishmania tropicaMaleCutaneous leishmaniasisKala azarLeishmaniasisPhlebotomus martiniPhlebotomus orientalisSand flyVisceral leishmaniasis

Identifiers

PMID41390012
PMCPMC13127117

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.