Evidence map›Paper›PMID 41389503›Full record

ArticleAddictive behaviors2026

Alcohol demand and alcohol use disorder among adolescents and young adults who drink heavily: An exploratory analysis including sex differences.

Kathryn S Gex, ReJoyce Green, Samuel F Acuff, Anna E Kirkland, Brittney D Browning, Rachel L Tomko, Kevin M Gray, Lindsay M Squeglia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathryn S GexMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA. Electronic address: soltisk@musc.edu.
ReJoyce GreenMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.
Samuel F AcuffRecovery Research Institute, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Anna E KirklandMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.
Brittney D BrowningMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.
Rachel L TomkoMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.
Kevin M GrayMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.
Lindsay M SquegliaMedical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA.

Funding

DRUG ABUSE TRAINING PROGRAMT32DA007288 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Christopher W Cowan, Rachel Penrod-Martin · 1991 to 2026
$11.8M
Clinical Scientists Training Program in Addictions at MUSCK12DA031794 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Kevin M. Gray, AIMEE L MCRAE-CLARK · 2013 to 2026
$7.2M
A Proof-of-Concept Trial of N-Acetylcysteine for Adolescent Alcohol Use DisorderR01AA027399 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GRAY, KEVIN M, SQUEGLIA, LINDSAY · 2018 to 2022
$3.5M
Neuroscience-informed Treatment Development for Adolescent Alcohol Use DisordersK23AA025399 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SQUEGLIA, LINDSAY · 2016 to 2020
$1.0M
Mentoring Clinical Investigators in Patient-Oriented Adolescent Alcohol ResearchK24AA031052 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Lindsay Squeglia · 2024 to 2026
$644k
Development of a Novel Cannabis Brief Intervention for Frequently-Using Emerging AdultsK23DA058077 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Kathryn Gex · 2024 to 2026
$616k
The effects of adolescent alcohol use on oral microbiota and the brainK01AA031745 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Anna E Kirkland · 2024 to 2026
$583k
NIAAA NIH HHS K01 AA031745NIAAA NIH HHS K23 AA025399NIAAA NIH HHS K24 AA031052NIAAA NIH HHS R01 AA027399NIDA NIH HHS K12 DA031794NIDA NIH HHS K23 DA058077NIDA NIH HHS T32 DA007288
6 · The paper itself

Abstract

Behavioral economic alcohol demand, or the reward value of alcohol consumption, consistently shows associations between alcohol use and alcohol use disorder (AUD) in adults, yet research within clinical youth populations (considered to be ages 15-24) remains limited. It is critical to better understand how demand functions in clinical youth populations to predict alcohol related outcomes. Moreover, given the narrowing gap between male and female youth in alcohol use prevalence in recent years, exploring sex differences in alcohol demand and its role in the relationship between demand, alcohol use, alcohol-related problems, and AUD is important. The current study used data from two samples of adolescents and young adults from the community (N = 127; ages 16-25, M

Indexed as

Alcohol DrinkingAlcoholismAlcohol-Related DisordersAdolescentAdultFemaleHumansMaleRewardSex FactorsUnderage DrinkingYoung AdultAdolescentsAlcoholBehavioral economic demandHypothetical purchase taskSex differencesYoung Adults

Identifiers

PMID41389503
PMCPMC12990203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.