ArticleNaunyn-Schmiedeberg's archives of pharmacology2026
Genetic diversity and antimicrobial resistance of clinical Acinetobacter baumannii isolates: insights from ERIC typing.
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Lineage-Specific Associations between the Resistome and Mobilome across 10,500 Globally DistributedComputational and structural biotechnology journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Acinetobacter baumannii is a major nosocomial pathogen, and multidrug-resistant (MDR) and extensively drug-resistant (XDR) isolates pose a serious threat to healthcare systems worldwide. Genetic diversity among clinical isolates contributes to variable resistance profiles, complicating treatment strategies and infection control efforts. In this study, 102 non-duplicate A. baumannii isolates were collected over 1 year from Shahid Beheshti Hospital, Kashan, Iran, predominantly from bronchoalveolar lavage samples. Antimicrobial susceptibility testing revealed high resistance rates against piperacillin/tazobactam (93.1%), meropenem (93.1%), and ciprofloxacin (91.2%), while tobramycin retained the highest in vitro activity. ERIC-PCR genotyping identified 38 distinct genotypes clustered into five groups, with clusters I-IV representing major lineages. Cluster I exhibited significantly higher resistance to meropenem, tobramycin, gentamicin, and ciprofloxacin compared to other clusters (p < 0.05), and overall, 64.8% of isolates were closely related, indicating clonal dissemination within the hospital. These findings demonstrate the coexistence of multiple XDR lineages and highlight a strong association between clonal types and antimicrobial resistance patterns. Integrating molecular surveillance with antibiotic stewardship and infection control measures is essential to limit the spread of MDR and XDR A. baumannii in healthcare settings.
Indexed as
Identifiers
41389350What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.