Evidence map›Paper›PMID 41389236›Full record

ArticleJournal of occupational rehabilitation2025

Assessing the Effect of a Rehabilitation Intervention on Exhaustion Disorders, Depression, and Return to Work: A Randomized Controlled Trial.

Emelie Thunqvist, Åke Nygren, Björn Löfman, David Parker, Emma Brulin

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of occupational rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05314530 (Validation of the ReTA-model), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05314530 naunknown statusnot on this map

Validation of the ReTA-model: Rehabilitation Trail for Workers on Long-term Sick Leave in the Healthcare

TypeinterventionalSponsorKarolinska InstitutetRan2022 to 2023Enrolled64ConditionsBurnoutArmsReTA-model
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emelie ThunqvistUnit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.
Åke NygrenDepartment of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
Björn LöfmanDepartment of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
David ParkerThe Back Institute, Pain and Stress Rehabilitation, Stockholm, Sweden.
Emma BrulinUnit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden. emma.brulin@ki.se.ORCID http://orcid.org/0000-0002-3374-268X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim was to evaluate the effect of a Rehabilitation to Work (ReTA) model on symptoms of exhaustion disorder (ED), depression, and return to work (RTW) among healthcare workers on long-term sickness absence (LTSA) for stress-related ill-health.

methodsThe ReTA was set up as a randomized control trial (RCT), including 30 in the intervention and 41 in the control group. Physicians and nurses on LTSA were recruited via a national insurance database. The degree of self-reported ED and depression was measured using the Karolinska Exhaustion Disorder Scale (KEDS), and the Montgomery Åsberg Depression Rating Scale (MADRS). Data was collected at baseline, 3-month, and 1-year follow-up. A linear mixed model and Pearson chi-square were used to examine between- and within-group differences in KEDS, MADRS, and RTW.

resultsAt baseline, no differences in KEDS and MADRS were observed between the groups. KEDS decreased significantly at the 3-month (m = 20.28, m = 25.93; p = 0.023) and 1-year (m = 19.78, m = 24.83; p = 0.041) follow-up in the intervention group but not in the control group (Intervention*time: F (2, 132.595) = 4.126, p = .018). The effect size at both follow-ups was moderate to large (Cohen's d = 0.77 0.69, respectively). No effect was found in MADRS. Between the 3-month and 1-year follow-ups for RTW, there was a significant change for the intervention group (p = 0.029), indicating an increase in full RTW.

conclusionThe ReTA model is an effective treatment for ED among healthcare professionals. Further research is needed with longer follow-up periods to see the long-term effects on ED, depression, and RTW. TRIAL REGISTRY: NCT05314530.

Indexed as

BurnoutDepressionExhaustion disorderHealth care professionalsRCTRehabilitationStress-related ill-health

Identifiers

PMID41389236

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.