Evidence map›Paper›PMID 41389146›Full record

ArticleInternational forum of allergy & rhinology2026

Impact of Sinus Surgery on Bacteriome Composition in Patients With Chronic Rhinosinusitis With Nasal Polyps.

Maria Vorobeva, Aleksandr iAkushev, Chien-Chang Chen, Masaki Orihara, Nadeem Akbar, Patrick Colley, Esha Sehanobish, Casper Ho Yin Chung, Allison Scott, Erin O'Brien and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Maria VorobevaDepartment of Allergy Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-6579-6869
Aleksandr iAkushevDepartment of Allergy Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0009-0001-7040-7792
Chien-Chang ChenDepartment of Allergy Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-2581-1830
Masaki OriharaDepartment of Allergy Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-8182-9800
Nadeem AkbarMontefiore Medical Center, The University Hospital For Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0001-6108-6985
Patrick ColleyMontefiore Medical Center, The University Hospital For Albert Einstein College of Medicine, Bronx, New York, USA.
Esha SehanobishAlbert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0003-1090-2991
Casper Ho Yin ChungDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0001-5868-7712
Allison ScottDepartment of Allergy Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0009-0000-5492-8937
Erin O'BrienDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-4891-9548
Connie B ChangDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0001-9555-8223
Hirohito KitaDivision of Allergy, Asthma and Clinical Immunology, Mayo Clinic, Scottsdale, Arizona, USA.ORCID https://orcid.org/0000-0002-6854-2936
Jovanka VoyichMontana State University, Bozeman, Montana, USA.ORCID https://orcid.org/0009-0004-0200-7123
Kathryn KnoopDepartment of Immunology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-2007-3066
Elina JerschowDepartment of Allergy Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-9066-2483

Funding

Clinical and Translational Science AwardKL2TR001071 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SHAMOON, HARRY · 2013 to 2017
$968k
Staphylococcus aureus and eicosanoid dysregulation as drivers of inflammation in aspirin-exacerbated respiratory diseaseR21AI171306 · NIAID · MAYO CLINIC ROCHESTER · PI JERSCHOW, ELINA · 2024 to 2025
$444k
NCATS NIH HHS CTSA 5KL2TR001071NCATS NIH HHS KL2 TR001071NCATS NIH HHS R21AI171306 to E.J.NIAID NIH HHS R21 AI171306NIH HHS
6 · The paper itself

Abstract

key pointsStaphylococcus aureus showed a significant increase in relative abundance in CRSwNP patients following endoscopic sinus surgery compared to pre-surgery samples. Other Staphylococcus species were found to correlate positively with S. aureus in patients with nasal polyps; among those, S. caprae correlated strongly while being the most represented in samples. Patients with recurrent nasal polyp growth exhibited a substantially greater postoperative increase in the relative abundance of S. aureus.

Indexed as

MicrobiotaNasal PolypsParanasal SinusesRhinitisSinusitisAdultAgedChronic DiseaseEndoscopyFemaleHumansMaleMiddle AgedRhinosinusitisStaphylococcal InfectionsStaphylococcus aureusmetagenomicsmicrobiomenasal polypssinus surgeryStaphylococcus aureus

Identifiers

PMID41389146
PMCPMC13108360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.