Evidence map›Paper›PMID 41389115›Full record

ArticleJournal of medical ultrasonics (2001)2026

Detection of fetal structural abnormalities at 20 and 30 weeks: a retrospective study of prenatal ultrasound screening.

Yuki Kamihara, Katsusuke Ozawa, Kohei Ogawa, Jin Muromoto, Rika Sugibayashi, Seiji Wada, Haruhiko Sago

Abstract read
In one paragraph

Article in Journal of medical ultrasonics (2001), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuki KamiharaCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan.
Katsusuke OzawaCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan. ozawa-kt@ncchd.go.jp.ORCID http://orcid.org/0000-0002-8728-5576
Kohei OgawaCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan.
Jin MuromotoCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan.
Rika SugibayashiCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan.
Seiji WadaCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan.
Haruhiko SagoCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the role of ultrasound screening for fetal structural abnormalities at 20 and 30 weeks' gestation.

methodsThis retrospective study included women with singleton pregnancies who underwent routine ultrasound screening at our hospital between May 2014 and April 2021. Participants received two ultrasound screening examinations: at 20 and 30 weeks' gestation. We evaluated the frequency and details of fetal structural abnormalities identified during each examination.

resultsA total of 10,560 pregnant women underwent ultrasound screening at 20 and 30 weeks' gestation and delivered at our hospital. Structural abnormalities were observed in 142 (1.3%) women; of note, screening examinations at 20 and 30 weeks detected 42.3% and 23.9% of cases, respectively. Routine point-of-care ultrasound examinations performed between 20 and 30 weeks and beyond 30 weeks detected 8.5% and 6.3% of cases, respectively, with 19.0% of cases identified after birth. Cleft lip and palate and ventricular septal defects (VSDs) were the most common abnormalities detected at the 20-week ultrasound screening. At the 30-week ultrasound screening, in addition to hydronephrosis, VSD, and vascular rings, which were also detected at the 20-week ultrasound screening, diaphragmatic hernia, ovarian cysts, achondroplasia, duodenal atresia, and meconium peritonitis, which could be apparent later in pregnancy, were detected.

conclusionsThe 20-week ultrasound screening revealed common fetal structural abnormalities, and the 30-week ultrasound screening detected fetal structural abnormalities that failed to be detected during the 20-week ultrasound screening and became apparent later in pregnancy. Adding a 30-week ultrasound screening provides enhanced diagnostic details in comparison to 20-week screening.

Indexed as

Congenital AbnormalitiesFetal DiseasesUltrasonography, PrenatalAdultFemaleGestational AgeHumansMiddle AgedPregnancyPregnancy Trimester, SecondRetrospective StudiesCongenital abnormalitiesFetal diseasesPrenatal diagnosisThird trimesterUltrasound screening

Identifiers

PMID41389115
PMCPMC13407442

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.