Evidence map›Paper›PMID 41388899›Full record

ArticleJournal of feline medicine and surgery2026

Effect of trauma on the concentration of selected feline acute phase proteins.

Eva Spada, Anna Zurlo, Liliana Carnevale, Luciana Baggiani, Chiara Giudice, Martina Manfredi, Jessica Bassi, Maurizio Longo, Daniela Proverbio, Mauro Di Giancamillo

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Acute Phase Proteins in Cats Naturally Infected or Seropositive forAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eva SpadaDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0000-0003-3898-6955
Anna ZurloDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0009-0005-6563-5335
Liliana CarnevaleDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0000-0002-5023-0782
Luciana BaggianiDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0009-0009-7240-303X
Chiara GiudiceDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0000-0001-9195-4085
Martina ManfrediDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.
Jessica BassiDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0009-0006-0776-8161
Maurizio LongoDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.
Daniela ProverbioDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0000-0003-3922-6069
Mauro Di GiancamilloDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.ORCID 0000-0003-3128-4619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesThe aim of the present study was to evaluate selected acute phase proteins (APPs) in 61 cats (mainly stray, domestic shorthair cats, aged 2 months to 17 years, 39 males and 22 females) presented with acute trauma at a university teaching hospital.MethodsSerum amyloid A (SAA), haptoglobin (Hp), ceruloplasmin and albumin were compared with APPs in a population of healthy cats with similar demographic data and in cats with trauma, considering demographic data, trauma type and localisation (craniofacial and/or vertebral and/or appendicular, thoracic, abdominal and localised, multiple or polytrauma), anti-inflammatory treatment and outcome (survival to discharge or death). APPs were correlated to age, rectal temperature, body weight, total leukocyte, neutrophil, band neutrophil and lymphocyte counts, total protein, albumin:globulin ratio, base excess and hospitalisation duration.ResultsIn cats with acute trauma, the median concentrations of SAA and Hp were significantly higher than in healthy control cats (90.5 vs 0.6 mg/ml and 130.7 vs 58.8 mg/dl, respectively;

Indexed as

Acute-Phase ProteinsCat DiseasesWounds and InjuriesAnimalsCase-Control StudiesCatsFemaleHaptoglobinsMaleAcute-Phase ProteinsHaptoglobinsAcute traumaalbuminceruloplasminhaptoglobinprognostic valueserum amyloid A

Identifiers

PMID41388899
PMCPMC12924940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.