Evidence map›Paper›PMID 41388840›Full record

ArticleJournal of cosmetic dermatology2025

Caffeinated Skincare Development and Optimization: Upcycling Spent Coffee Grounds Into Natural Exfoliants.

Alisa Elezović, Belma Pehlivanović Kelle, Amila Oras, Hava Mujkić, Meldina Memić, Elis Kojčin, Merima Bulbulušić, Alen Mujčinović, Aleksandra Nikolić, Fahir Bečić

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alisa ElezovićDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.ORCID https://orcid.org/0000-0003-0559-1463
Belma Pehlivanović KelleDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.ORCID https://orcid.org/0000-0002-1574-493X
Amila OrasDepartment of Food Technologies, Faculty of Agriculture and Food Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Hava MujkićDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Meldina MemićDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Elis KojčinDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Merima BulbulušićDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Alen MujčinovićDepartment of Agri-Food Economics, Faculty of Agriculture and Food Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Aleksandra NikolićDepartment of Agri-Food Economics, Faculty of Agriculture and Food Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Fahir BečićDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Funding

Ministry of Science, Higher Education and Youth of Sarajevo Canton, Bosnia and Herzegovina 27-02-35-31288-1/24
6 · The paper itself

Abstract

backgroundSpent coffee grounds (SCG) offer significant ecological and cosmetic potential. The conversion of SCG into safe and efficient cosmetic products promotes all aspects of sustainability and circular practices within the cosmetic industry.

aimsThis study aimed to show the interdisciplinary bottom-up approach within two focal points: demonstrating the use of upcycled materials in high-value natural products and understanding how base formulations' content and properties influence the characteristics, consumer preferences, and clinical efficacy of exfoliant products.

methodsMethods included characterization of SCG, development of formulations, physicochemical characterization, stability testing, and the estimation of carbon dioxide emissions of the preparation process. Consumer panel testing optimized the most preferred sensory characteristics of exfoliant products chosen for clinical evaluation. Transepidermal water loss measurements assessed skin barrier disruption and recovery after the use of exfoliant formulations and after the application of hand cream.

resultsThe SCG found richest in bioactive substances was incorporated in three concentrations into seven exfoliant formulation bases. Stable formulations were assessed by a consumer panel, and four formulations with the best sensory characteristics were ointment-based (F1) with 5% and 10% SCG, cream-based (F6), and gel-based (F11) with 5% SCG. The ointment-based exfoliant showed no significant changes after application or after hydration cream. Aqueous formulations (F6 and F11) temporarily disrupted skin barrier function, but full recovery occurred within 6 h of hand cream application.

conclusionBy utilizing SCG, high-quality cosmetic formulations can be created that are well-received by consumers. Clinical findings suggest that different exfoliant formulations may suit various skin types.

Indexed as

CaffeineCoffeeCosmeticsSkin CareAdministration, CutaneousAdultConsumer BehaviorFemaleHumansSkinSkin CreamWater Loss, InsensibleCaffeineCoffeeCosmeticsenvironmental impactexfoliant formulationskin sensory assessmentspent coffee groundstransepidermal water loss

Identifiers

PMID41388840
PMCPMC12701547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.