Evidence map›Paper›PMID 41388739›Full record

ArticlePlant biotechnology journal2026

Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50-JAZ5 Module.

Chuang Liu, Zhen Liu, Xia Li, Yating Chen, Ronghui Sun, Peijie Li, Qianqian Feng, Yuanhua Wang, Jie Ren, Qian Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chuang LiuDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.ORCID https://orcid.org/0009-0006-8131-9073
Zhen LiuDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.
Xia LiDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.
Yating ChenDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.
Ronghui SunDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.
Peijie LiDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.
Qianqian FengDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0001-7800-1626
Yuanhua WangJiangsu Vocational College of Agriculture and Forestry, Jurong, China.
Jie RenTobacco Research Institute of Chinese Academy of Agricultural Sciences, Qingdao, China.
Qian LiDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.
Bingbing LiDepartment of Pomology, College of Horticulture, China Agricultural University, Beijing, China.

Funding

2115 Talent Development Program of China Agricultural UniversityBeijing Rural Revitalization Agricultural Science and Technology Project NY2401150124National Key R&D Program of China 2023YFF1001700National Key Research and Development Program of China 2022YFD2100102-3National Natural Science Foundation of China 32222074
6 · The paper itself

Abstract

Colletotrichum spp., hemibiotrophic fungal pathogens, threaten global strawberry production. Jasmonate (JA) regulates plant-Colletotrichum interactions, but its mechanisms remain unclear. Here we demonstrate that both exogenous methyl jasmonate (MeJA) treatment and elevated endogenous MeJA levels increase strawberry susceptibility to anthracnose. Two key JA biosynthesis genes, FveAOS2 and FveAOC3, were identified as contributors to Colletotrichum-induced susceptibility. Further analysis revealed that the FveSnRK2.1-FveWRKY50 phosphorylation module functions as an important molecular switch in regulating disease susceptibility. Specifically, Colletotrichum infection or MeJA application activates FveSnRK2.1, which phosphorylates FveWRKY50 at serine residue 88 (S88). This phosphorylation enhances the stability and transcriptional activity of FveWRKY50, leading to increased expression of FveAOS2 and FveAOC3, higher MeJA accumulation and enhanced susceptibility. Notably, the strawberry JASMONATE-ZIM DOMAIN (JAZ) protein FveJAZ5 suppresses susceptibility by directly interacting with FveWRKY50, thereby preventing its interaction with FveSnRK2.1 and inhibiting the activation of FveAOS2 and FveAOC3. Upon pathogen attack or MeJA signalling, FveJAZ5 is degraded, thereby releasing FveWRKY50 from suppression. The study elucidates a Colletotrichum-induced 'JA signaling - JA biosynthesis' positive feedback loop that drives strawberry susceptibility. Knocking out FveWRKY50 and overexpressing FveJAZ5 generated anthracnose-resistant germplasms. These findings deepen understanding of plant-Colletotrichum interactions and provide genes for resistant strawberry breeding.

Indexed as

AcetatesColletotrichumCyclopentanesFragariaOxylipinsPlant DiseasesPlant ProteinsDisease ResistanceGene Expression Regulation, PlantPhosphorylationPlant Growth RegulatorsTranscription FactorsAcetatesCyclopentanesjasmonic acidmethyl jasmonateOxylipinsPlant Growth RegulatorsPlant ProteinsTranscription FactorsJAZ5MeJASnRK2.1strawberry anthracnoseWRKY50

Identifiers

PMID41388739
PMCPMC13140450

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.