Evidence map›Paper›PMID 41388710›Full record

ArticlePlant biotechnology journal2026

PPSR1 Protein Functions as an Important Regulator to Enhance Plant Growth Performance Under N, P, and K Deficient Stress Conditions.

Jieyu Chen, Chuanhezi Quan, Yang Zhao, Imani L D S Kalumith, Zhangjun Fei, Leon V Kochian, William J Lucas, Byung-Kook Ham

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jieyu ChenDepartment of Plant Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0001-6691-5404
Chuanhezi QuanDepartment of Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0009-0000-0121-2679
Yang ZhaoDepartment of Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Imani L D S KalumithDepartment of Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0009-0000-2077-4351
Zhangjun FeiBoyce Thompson Institute, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0001-9684-1450
Leon V KochianDepartment of Plant Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0003-3416-089X
William J LucasDepartment of Plant Biology, University of California, Davis, California, USA.ORCID https://orcid.org/0000-0003-4714-7491
Byung-Kook HamDepartment of Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0002-7283-9150

Funding

Canada Excellence Research Chair for Food Systems and SecurityCanada Foundation for Innovation CFI#38103Natural Sciences and Engineering Research Council of Canada #RGPIN-2019-04421New Frontiers in Research Fund NFRFE-2020-01108
6 · The paper itself

Abstract

Phosphorus (P) is an essential macronutrient for various biological processes in plant growth. Modern agricultural science has advanced the knowledge of regulatory mechanisms underlying phosphorus starvation responses (PSRs), aiming to develop phosphate-efficient crops with sustainable production under reduced Pi fertilizer application. However, information regarding coordinated shoot and root adaptations in response to combined nutrient stresses is limited. This study investigated the role of Phloem Phosphate Stress Repressed 1 (PPSR1) in modulating PSRs and other nutrient deficiency adaptations. The Arabidopsis functional homologue of Cucumis sativus PPSR1 (CsPPSR1), designated AtPPSR1, was identified. AtPPSR1 encodes a glycine-rich domain-containing protein, and its ectopic expression confers enhanced growth performance to plants. Transcriptomic analyses revealed AtPPSR1 as a regulatory mediator of PSRs, photosynthesis, and root development. AtPPSR1 interacted with PHOSPHATE STARVATION RESPONSE 1 (PHR1) to regulate PHR1-target genes for adaptive root development in response to Pi-starvation stress. Additionally, AtPPSR1 was graft-transmissible, and shoot-borne AtPPSR1 played a role in restoring the root phenotype of the ppsr1 mutant. Physiological analyses revealed that enhanced AtPPSR1 expression enabled resilience to nitrogen (N) and potassium (K)-starvation, as well as to Pi-deficiency. Furthermore, we identified homologues of CsPPSR1 and AtPPSR1 in Brassica napus (canola), which displayed similar expression patterns in response to Pi-starvation stress. Overexpression of PPSR1, identified from Arabidopsis, cucumber, and canola, improved growth performance and seed production in canola under N-, Pi-, or K-deficient conditions, within the controlled environment. These findings provide novel insights into PPSR1-mediated molecular coordination to enhance plant resilience to mineral nutrient deficiency.

Indexed as

ArabidopsisArabidopsis ProteinsNitrogenPhosphorusPlant ProteinsPotassiumCucumis sativusGene Expression Regulation, PlantPhosphatesPlant RootsPlants, Genetically ModifiedStress, PhysiologicalArabidopsis ProteinsNitrogenPhosphatesPhosphorusPlant ProteinsPotassiumnutrient efficiencyphosphorus starvation responsePHR1PPSR1shoot‐root coordination

Identifiers

PMID41388710
PMCPMC13140395

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.