Evidence map›Paper›PMID 41388667›Full record

ArticlePlant communications2026

The OsWRKY47-OsMYB30/OsWRKY39 module confers both physical and chemical defenses against Magnaporthe oryzae to enhance rice blast resistance.

Yuchen Liu, Jun Xiong, Qiuxin Wu, Kang Wang, Junjie Yin, Qingqing Hou, Kaiwei He, Tianyu Zhou, Ying Zhang, Junjie Chen and 18 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Plant communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Yuchen LiuNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Jun XiongNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Qiuxin WuNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; State Key Laboratory of Tropical Crop Breeding, Rubber Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101, China.
Kang WangNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Junjie YinNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Qingqing HouNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Kaiwei HeNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Tianyu ZhouNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Ying ZhangNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Junjie ChenNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Liting XuNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Jia ZengNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Yahuan MaNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Qian YiNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Wei ZhangNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Langqing ChenNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Yongyan TangNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Xiang LuNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Long WangNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Xiaobo ZhuNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Jia SuNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Hui ShiNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Li SongNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Qing XiongNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Jing WangNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Min HeNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
Xuewei ChenNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China. Electronic address: xwchen88@sicau.edu.cn.
Weitao LiNew Cornerstone Science Laboratory, State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China. Electronic address: weitao-li@sicau.edu.cn.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

The infection cycle of Magnaporthe oryzae (M. oryzae) in rice typically involves initial invasion through penetration of the leaf epidermis, followed by expansion into neighboring cells. However, few studies have identified single genes that mediate defense against both invasion and expansion. In this study, we demonstrate that OsWRKY47 positively regulates resistance to both stages of M. oryzae infection. Mechanistic analyses indicate that OsWRKY47 transcriptionally activates OsMYB30 during the early stage, thereby enhancing lignin accumulation and strengthening physical barriers against fungal invasion. At later stages, OsWRKY47 represses OsWRKY39 expression, thereby inhibiting M. oryzae expansion. Knockout of OsWRKY39 leads to increased accumulation of stevioside, a metabolite that activates plant immune responses, representing a chemical defense strategy. Structure-function analyses further reveal that a region comprising amino acids 282-288 of OsWRKY47 is crucial for the positive regulation of OsMYB30, whereas the region comprising amino acids 303-333 is essential for repression of OsWRKY39. Collectively, these findings reveal an OsWRKY47-OsMYB30/OsWRKY39 regulatory module that confers resistance to M. oryzae by coordinating physical and chemical defenses to restrict pathogen invasion and expansion. Such coordinated activation of physical and chemical defenses may represent a widespread strategy in plant pathogen responses.

Indexed as

AscomycotaDisease ResistanceMagnaportheOryzaPlant DiseasesPlant ProteinsTranscription FactorsGene Expression Regulation, PlantPlant ProteinsTranscription FactorsligninMagnaporthe oryzaeMYBresistancesteviosideWRKY

Identifiers

PMID41388667
PMCPMC12903394

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.