Evidence map›Paper›PMID 41388614›Full record

ArticleAnnals of medicine2025

LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study.

Juan Wang, Chao Li, Guanghai Wu, Jing Xu

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Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan WangDepartment of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.
Chao LiDepartment of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.
Guanghai WuDepartment of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.
Jing XuDepartment of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have identified various roles for long non-coding RNAs (lncRNAs) in cancer progression. However, an in-depth understanding of the regulatory mechanisms of lncRNAs in colorectal cancer (CRC) and their diagnostic significance is rather limited. MATERIALS AND

methodsThe diagnostic value of LBX2 antisense RNA 1 (LBX2-AS1) was assessed using public databases and clinical samples. Cell-counting kit 8 (CCK-8), Colony Formation, transwell, and wound scratch assays were performed to assess CRC cell proliferation and metastasis

resultsAs a marker of poor prognosis, LBX2-AS1 was highly expressed in CRC tumor tissues and cells (all

conclusionThis study demonstrates that LBX2-AS1 promotes CRC angiogenesis and activates the glycolysis

Indexed as

Colorectal NeoplasmsMicroRNAsNeovascularization, PathologicRNA, Long NoncodingAngiogenesisAnimalsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticGlycolysisHumansMaleMiceMice, Inbred BALB CMice, NudeMicroRNAsRNA, Long Noncodingangiogenesiscolorectal cancerglycolysisLBX2-AS1midkinemiR-491-5p

Identifiers

PMID41388614
PMCPMC12704118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.