Evidence map›Paper›PMID 41388500›Full record

ReviewStem cell research & therapy2025

Development of mesenchymal stem cells: therapeutic effect and prospect for rheumatoid arthritis.

Wenyue Jia, Te Ba, Yuqi Liu, Haizhu Jin, Yumeng Zhang, Ze Wang, Yang Liu, Huiqin Hao

Abstract readReview
In one paragraph

Review in Stem cell research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenyue JiaShanxi University of Chinese Medicine, Jinzhong, 030619, China.
Te BaShanxi University of Chinese Medicine, Jinzhong, 030619, China.
Yuqi LiuShanxi University of Chinese Medicine, Jinzhong, 030619, China.
Haizhu JinShanxi University of Chinese Medicine, Jinzhong, 030619, China.
Yumeng ZhangShanxi University of Chinese Medicine, Jinzhong, 030619, China.
Ze WangShanxi University of Chinese Medicine, Jinzhong, 030619, China.
Yang LiuShanxi University of Chinese Medicine, Jinzhong, 030619, China. liuyang1980@sxtcm.edu.cn.
Huiqin HaoShanxi University of Chinese Medicine, Jinzhong, 030619, China. hhq@sxtcm.edu.cn.

Funding

National Natural Science Foundation of China 82474387
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, and it cannot be cured currently. Mesenchymal stem cells (MSCs), an emerging therapeutic method, have been applied to treat RA. It is essential to learn more about RA and MSCs. A total of 1,296 records were retrieved from the Web of Science. Then, Citespace and VOSviewer were used for the scientometric analysis of the data, including national distribution, institutional distribution, author distribution, journals, funding, and keywords. Our analysis presents basic information on the research into treating RA with MSCs, identifies research hotspots, and outlines clear research directions for interested researchers. At present, research on MSCs and RA focuses on the diversity of therapeutic effects, inflammatory mechanisms, molecular mechanisms of MSCs from different sources, and extracellular vesicles of MSCs on RA. Cutting-edge research in this field is booming, and this study will promote the development of the scientific research and clinical applications of MSCs in treating RA.

Indexed as

Arthritis, RheumatoidMesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsHumansDevelopmentMesenchymal stem cellsResearch hotspotsRheumatoid arthritisWeaknesses

Identifiers

PMID41388500
PMCPMC12817875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.