SynthesisBMC neurology2025
Prevalence of depression in post-stroke aphasia: systematic review and meta-analysis.
Synthesis in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- "Then you are left on your own": barriers to guideline-based speech and language therapy for aphasia along the patient journey in the German-speaking healthcare context.BMC health services research · 2026Article
- Article
- Prevalence and factors associated with post-stroke depression: a cross-sectional analysis of a prospectively assembled cohort in Eastern Saudi Arabia.Frontiers in neurology · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundDepression is a significant consequence of post-stroke aphasia, adversely affecting quality of life; however, its frequency remains unclear. The objective of this systematic review and meta-analysis is to quantify depression prevalence rates among individuals with post-stroke aphasia.
methodsWe systematically reviewed studies on depression in post-stroke aphasia, conducting a meta-analysis that focused on the frequency of depression using diagnostic tools. We conducted a systematic search to identify studies reporting original data on depression frequency in individuals with post-stroke aphasia. From each included study, we extracted data on patient characteristics, diagnostic methods, and aphasia-friendliness. The quality of each study was assessed to ensure reliability and accuracy. We estimated the pooled prevalence using random effect models.
resultsSixteen articles, conducted between 1993 and 2023, met our inclusion criteria. The pooled prevalence of post-stroke depression in people with aphasia was 31.7% (95% CI = 0.2354, 0.4044). Self-reports were the most common method for assessing depression, with participants’ average time post-stroke onset being 1.75 years (range = 0.02–6.76 years). Our meta-analysis found no significant difference in depression prevalence between self-reported and proxy-reported measures, nor any effect of time post-stroke onset on depression.
conclusionsDepression is a common concern in post-stroke aphasia. The lack of observed effects from assessment method or time since stroke may be due to methodological inconsistencies in reporting across studies. Psychometrically sound assessment tools validated for people with aphasia, along with more consistent reporting of patient characteristics, are essential for improving depression screening and mental health care in this population.
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