ArticleBMC oral health2025
Predictors of systemic complications and prolonged hospitalization in odontogenic infections: a 12-year retrospective analysis of 997 cases.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOdontogenic infections remain a frequent cause of hospitalization and can progress to systemic complications with substantial resource use. Reliable risk stratification is needed to guide early management. Therefore, this study aimed to identify independent risk factors for systemic complications and prolonged hospitalization in odontogenic infections, and to examine trends in case frequency over a 12-year period.
methodsA retrospective analysis of 997 surgically treated inpatient cases from 2012 to 2023 was conducted. Clinical outcomes of interest were systemic complications and prolonged hospitalization (≥ 10 days). Associations with clinical and demographic variables were evaluated using bivariate and multivariable logistic regressions. Multivariable models were validated by bootstrap resampling and receiver operating characteristic analyses. Case volume trends were analyzed using Poisson and negative binomial regression models.
resultsAnnual hospitalization rates for odontogenic infections increased significantly over the study period (IRR 1.043; 95% CI: 1.025-1.063; p < 0.001), despite an overall decline in inpatient admissions. Systemic complications occurred in 3.8% of cases and were independently associated with age (aOR: 1.040 per year; 95% CI: 1.019-1.061; p < 0.001), COPD (aOR: 3.707; 95% CI: 1.569-8.761; p = 0.003), chronic alcohol addiction (aOR: 5.625; 95% CI: 2.270-13.937; p < 0.001), and multi-space involvement (aOR: 5.492; 95% CI: 2.379-12.681; p < 0.001). Prolonged hospitalization occurred in 6.7% and was independently predicted by multi-space involvement (aOR: 8.381; 95% CI: 4.390-16.000; p < 0.001).
conclusionsAge, COPD, chronic alcohol addiction, and multi-space involvement independently predict systemic complications in odontogenic infections. Multi-space involvement also identifies patients at risk for prolonged hospitalization. The increasing burden of odontogenic infections highlights the need for a clinical risk score to enable early risk stratification, guide triage, and improve interdisciplinary management while reducing treatment costs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.