Evidence map›Paper›PMID 41388213›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

Mitral regurgitation and in-hospital outcomes of percutaneous left atrial appendage closure.

Gilad Margolis, Lior Haim, Adam Folman, Mark Kazatsker, Ariel Roguin, Eran Leshem

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gilad Margolis *Division of Cardiovascular Medicine, Hillel Yaffe Medical Center, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel. giladm@hymc.gov.il.
Lior Haim *Division of Cardiovascular Medicine, Hillel Yaffe Medical Center, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Adam FolmanDivision of Cardiovascular Medicine, Hillel Yaffe Medical Center, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Mark KazatskerDivision of Cardiovascular Medicine, Hillel Yaffe Medical Center, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Ariel RoguinDivision of Cardiovascular Medicine, Hillel Yaffe Medical Center, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Eran LeshemDivision of Cardiovascular Medicine, Hillel Yaffe Medical Center, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSignificant mitral regurgitation (MR), is associated with unfavorable perioperative and periprocedural outcomes in patients undergoing cardiac and noncardiac interventions. This may be especially important in left atrial procedures. However, information regarding its impact on percutaneous left atrial appendage closure (LAAC) procedures is scarce.

methodsWe utilized the National Inpatient Sample (NIS) database to identify patients who underwent percutaneous LAAC and had an MR diagnosis between the years 2016 and 2021 in the US, using ICD-10 codes. Clinical and sociodemographic data, in-hospital procedures and outcomes were collected. Baseline characteristics and outcomes were compared between patients with and without MR. Multivariable logistic regression models were used to identify predictors of in-hospital complications.

resultsAn estimated total of 123,785 patients underwent percutaneous LAAC between 2016 and 2021 in the US. Of them, 7,325 (5.9%) patients had an MR diagnosis. Compared to non-MR patients, MR patients were older and had higher CHA

conclusionIn patients undergoing percutaneous LAAC, MR was independently associated with an increased risk for AKI, but not for cardiac and vascular complications or in-hospital mortality in a US nationwide, all-comer registry.

Indexed as

In-hospital outcomesMitral regurgitationPercutaneous left atrial appendage closure

Identifiers

PMID41388213

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