ArticleNPJ microgravity2025
Superfood potential of Chlorella vulgaris: productivity and antioxidant boost under simulated moon and microgravity conditions.
Article in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Mechatronics Design of a Clinostat Agriculture Space System for Biomimetic Phyto-Growth in Microgravity (Phyto-G) and 3D-Motion Computer Simulation on Hydroponic Environment.Biomimetics (Basel, Switzerland) · 2026Article
- Growth of phylogenetically diverse microalgae under Far-Red light enriched spectra: implication for space missions' sustainability.Frontiers in microbiology · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
As space missions extend to the Moon and beyond, Bioregenerative Life Support Systems (BLSS) are vital for food, oxygen, and resource recycling in closed habitats. We examined the physiological, biochemical, and lipidomic responses of Chlorella vulgaris (CCALA 269) grown under simulated Earth gravity (1 g), Moon gravity (0.17 g), and microgravity (μg) using a 3D clinostat. Reduced gravity was associated with higher biomass, photosynthetic pigments, and antioxidant capacity. Cultures under lunar and microgravity showed up to 170% more chlorophyll and carotenoids, and 160% more polyphenols and antioxidant activity. Lipidomics revealed membrane remodeling, with higher galactolipids and triacylglycerols, suggesting adaptations to preserve membrane function and energy reserves. These responses indicate substantial physiological plasticity in C. vulgaris, suggesting its potential relevance for BLSS as a source of nutrient-rich biomass, oxygen, and antioxidants. Our results suggest its potential for space food and life support, and the need for further research under real partial gravity conditions.
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Registered trials
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