Evidence map›Paper›PMID 41387738›Full record

ArticleNature communications2025

Ethylene promotes branch formation but inhibits tendril development in cucumber.

Xiaofei Zhang, Tong Zhu, Wei Zhang, Yajing Zhang, Jian Zhang, Jingjing Yang, Changxuan Xia, Hong Zhao, Yongtao Yu, Changlong Wen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaofei Zhang *Beijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Tong Zhu *Beijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Wei ZhangBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Yajing ZhangBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Jian ZhangBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Jingjing YangBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Changxuan XiaBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Hong ZhaoBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Yongtao YuBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China.
Changlong WenBeijing Vegetable Research Center (BVRC), Beijing Academy of Agriculture and Forestry Sciences, State Key Laboratory of Vegetable Biobreeding, National Engineering Research Center for Vegetables, Beijing, China. wenchanglong@nercv.org.ORCID http://orcid.org/0000-0002-6154-922X

Funding

Beijing Academy of Agricultural and Forestry Sciences (BAAFS) JKZX202207
6 · The paper itself

Abstract

Ethylene coordinates numerous plant growth processes, particularly in cucurbit crops, yet its role in vegetative growth regulation remains largely unexplored. Here, we report the function of ethylene in controlling branch and tendril development in cucumber. We find that ethylene promotes branches formation but inhibits tendrils development in a dose-dependent manner. CRISPR-Cas9-generated gene-edited Csein2 and Csein3/Cseil1 mutants exhibit few branches and more tendrils. Exogenous ethylene can recover the branch/tendril defective phenotypes of the Csein3 and Cseil1 mutants but not those of the Csein2 mutant or the Csein3/Cseil1 double mutant. Transcriptomic and metabolic analyses reveal that CsCYP707A4 and CsTL are the key downstream targets of ethylene signaling. We show that CsEIN3 can bind to its promoters to activate the expression of CsCYP707A4 but inhibit the expression of CsTL, which leads to the opposite effect on branch and tendril development. The study sets the foundation for designing ideal plant architecture to increase production efficiency.

Indexed as

Cucumis sativusEthylenesPlant Growth RegulatorsCRISPR-Cas SystemsGene Expression Regulation, PlantMutationPlant ProteinsPromoter Regions, GeneticSignal TransductionethyleneEthylenesPlant Growth RegulatorsPlant Proteins

Identifiers

PMID41387738
PMCPMC12820186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.