ArticleActa obstetricia et gynecologica Scandinavica2026
Longitudinal maternal hemodynamics from late pregnancy to postpartum in uncomplicated twin pregnancies-A glimpse into long-term cardiovascular risk?
Article in Acta obstetricia et gynecologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Acute Left Heart Failure in Twin Pregnancies: Clinical Characteristics and Outcomes-A 10‑Year Retrospective Analysis of 24 Cases.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Longitudinal maternal hemodynamics from late pregnancy to postpartum in uncomplicated twin pregnancies-A glimpse into long-term cardiovascular risk?Acta obstetricia et gynecologica Scandinavica · 2026Article
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8 authors.
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Abstract
introductionTwin pregnancies impose greater cardiovascular demands than singleton gestations, potentially increasing long-term cardiovascular risk even in the absence of hypertensive disorders. Nevertheless, longitudinal assessments of maternal hemodynamics in uncomplicated twin pregnancies remain limited, and most available studies focus solely on the antenatal period. Chorionicity has been shown to markedly influence cardiovascular adaptation during twin gestation. This study aimed to investigate whether distinct hemodynamic adaptations occur in twin compared with singleton pregnancies during late gestation, 1 day and 6 weeks postpartum. MATERIAL AND
methodsIn this prospective longitudinal cohort study conducted at Hannover Medical School from 08/24 to 05/2025, 36 women with twin pregnancies (8 monochorionic (MC), 28 dichorionic (DC)) and 37 with singleton pregnancies underwent noninvasive hemodynamic assessment at 34 weeks' gestation, 1 day postpartum, and 6 weeks postpartum.
resultsMC twin pregnancies exhibited significantly higher cardiac output (MC: 7.72 L/min; DC: 5.62 L/min; S: 6.27 L/min; p = 0.01) and lower systemic vascular resistance (MC: 958.83 dynes × s/cm
conclusionsMonochorionic twin pregnancies are characterized by elevated cardiac output and reduced vascular resistance in late pregnancy, with a similar hemodynamic pattern appearing to persist in the postpartum period. This persistent cardiovascular strain may underlie the elevated short-term cardiovascular risk observed after twin births. Our findings highlight the need for larger longitudinal studies to explore the transition from physiological adaptation to potential cardiovascular maladaptation.
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