Evidence map›Paper›PMID 41387303›Full record

Trial reportInternational journal of dental hygiene2026

Efficacy and Safety of AirFloss Ultra With Essential Oils Versus Waxed Dental Floss as Adjunct to Toothbrushing: A Randomised Controlled Clinical Trial.

Tim M J A Thomassen, Dagmar E Slot, Therese A Elkerbout, Eveline van der Sluijs, Fridus A Van der Weijden

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in International journal of dental hygiene, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tim M J A ThomassenDepartment of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0003-2633-3236
Dagmar E SlotDepartment of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0001-7234-0037
Therese A ElkerboutDepartment of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0001-6713-6461
Eveline van der SluijsDepartment of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0003-1269-1710
Fridus A Van der WeijdenDepartment of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-5075-8384

Funding

Royal Philips N.V.
6 · The paper itself

Abstract

aimThis study aims to determine the efficacy and safety of AirFloss Ultra with essential oils (AFeo) compared to waxed dental floss (DF) as an adjunct to regular manual toothbrushing. MATERIAL AND

methodsThis study employed a randomly assigned, parallel, examiner-blind design. Eighty-two systemically healthy, right-handed volunteers with ≥ 25% gingival bleeding in the lower jaw but without periodontitis were enrolled. After 3 weeks of experimentally induced gingivitis, gingivitis reversal was assessed over the following 4 weeks. Subjects were divided into two groups: one used AFeo in addition to twice-daily manual toothbrushing with fluoride toothpaste, while the other used DF with the same brushing regimen. Bleeding On Marginal Probing (BOMP), Modified Silness and Löe Plaque Index (MPI), and approximal gingival abrasion scores (GAS) were recorded. These clinical parameters were analysed at baseline, intermediate time points, and study conclusion using appropriate parametric and non-parametric statistical methods.

resultsThe AFeo and DF groups showed a reduction in mean BOMP, MPI, and GAS scores. There were no significant differences in these parameters between the AFeo and DF groups at any time point (p > 0.05). Furthermore, no serious adverse events were reported.

conclusionNo significant difference in efficacy was observed between the AirFloss Ultra filled with an essential oil solution and waxed dental floss when used alongside manual toothbrushing. This conclusion is based on assessments of gingival bleeding, dental plaque, and gingival abrasion scores in the lower jaw following experimentally induced gingivitis. Both products were also found to be safe for use.

Indexed as

Dental Devices, Home CareGingivitisOils, VolatileToothbrushingAdultDental PlaqueDental Plaque IndexFemaleHumansMaleMiddle AgedPeriodontal IndexSingle-Blind MethodToothpastesTreatment OutcomeWaxesOils, VolatileToothpastesWaxesAirFlossdental flossdental plaquegingival abrasiongingival bleedinggingivitis

Identifiers

PMID41387303
PMCPMC12748044

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.