Evidence map›Paper›PMID 41387267›Full record

ArticleAdvanced healthcare materials2026

Spherical Skin Model: Stratified Co-Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening.

Elisa Lenzi, Nadia Vertti-Quintero, Julien Husson, Anne-Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N Baroud

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisa LenziInstitut Pasteur, Université Paris Cité, Physical Microfluidics and Bioengineering Unit, Paris, France.ORCID https://orcid.org/0000-0001-7756-0346
Nadia Vertti-QuinteroLVMH Recherche, 185 avenue de Verdun, Saint Jean de Braye, 45804, France.ORCID https://orcid.org/0000-0003-2312-982X
Julien HussonLaboratoire d'Hydrodynamique (LadHyX), CNRS, Ecole Polytechnique, Institut Polytechnique de Paris, Palaiseau, France.
Anne-Laure BulteauLVMH Recherche, 185 avenue de Verdun, Saint Jean de Braye, 45804, France.
Carine NizardLVMH Recherche, 185 avenue de Verdun, Saint Jean de Braye, 45804, France.
Karl PaysLVMH Recherche, 185 avenue de Verdun, Saint Jean de Braye, 45804, France.
Sébastien SartInstitut Pasteur, Université Paris Cité, Physical Microfluidics and Bioengineering Unit, Paris, France.ORCID https://orcid.org/0000-0002-4720-4671
Charles N BaroudInstitut Pasteur, Université Paris Cité, Physical Microfluidics and Bioengineering Unit, Paris, France.ORCID https://orcid.org/0000-0001-5414-2010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced skin models are critical for pursuing non-animal approaches in drug and cosmetic testing. However, existing 3D models remain complex and time-consuming, which limits their adoption. Spherical skin model (SSM) is presented, a platform that balances biological fidelity with experimental robustness. The SSM is based on a core-shell structure where the dermal core is modeled by embedding human fibroblasts into collagen microcarriers (150

Indexed as

FibroblastsKeratinocytesModels, BiologicalSkinApoptosisCell DifferentiationCoculture TechniquesHumansMicrospheresOxidative Stresscollagen beadscore‐shellhigh throughputskin

Identifiers

PMID41387267
PMCPMC13058795

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.