Evidence map›Paper›PMID 41387097›Full record

ArticleJournal of the American Geriatrics Society2026

Perioperative Optimization of Frail Older Adults Undergoing Elective Colorectal Surgery.

Rebecca Tang, Masaya Higuchi, Sarah E Rudasill, Praachi Raje, Jasmine J Johnson, Rory V Mather, Grace C Lee, Matthew Russell, Sindhura Pulluru, Christy Cauley and 2 more

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Rethinking the Integration of Artificial Intelligence Into Surgery: Centralized Risk Assessment for System-Level Impact.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rebecca TangDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0009-0007-4315-1211
Masaya HiguchiDivision of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Sarah E RudasillDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-9586-3209
Praachi RajeDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jasmine J JohnsonDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Rory V MatherDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Grace C LeeDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Matthew RussellDivision of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Sindhura PulluruDivision of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Christy CauleyDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Rocco RicciardiDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Hiroko KunitakeDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.

Funding

Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
RESEARCH TRAINING IN ALIMENTARY TRACT SURGERYT32DK007754 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HODIN, RICHARD A. · 1997 to 2025
$6.5M
Neuroimaging Training ProgramT32EB001680 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BRUCE R ROSEN · 2003 to 2026
$3.8M
Identifying a Novel Opioid-Specific EEG Biomarker That Can Be Targeted to Improve Patient Pain- and Opioid-Related OutcomesF30DA062465 · NIDA · HARVARD MEDICAL SCHOOL · PI MATHER, VU NGUYEN · 2025 to 2025
$55k
NIBIB NIH HHS T32 EB001680NIDA NIH HHS F30 DA062465NIDDK NIH HHS T32DK007754NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

backgroundThe Perioperative Optimization of Senior Health (POSH) clinic was established to address vulnerabilities and improve outcomes in frail older patients. This study describes the results of comprehensive perioperative optimization by the POSH interdisciplinary team (IDT) in patients who underwent colorectal surgery.

methodsFrail patients planned for colorectal surgery and enrolled in the POSH clinic (10/2021-09/2023) were retrospectively identified. Descriptive statistics were used to summarize the findings of preoperative geriatric assessment and postoperative outcomes. Outcomes were compared with a contemporary propensity-matched cohort using chi-squared analysis and two-sample t-tests for categorical and continuous variables, respectively.

resultsThirty-six patients with a median age of 80 years and a mean Charlson Comorbidity Index of 6.11 were planned for colorectal surgeries, most commonly colectomy (62.1%) and ostomy reversal (20.7%). Twenty-nine patients underwent surgical management after interdisciplinary optimization in the POSH clinic. The most common interventions recommended included advance care planning (86.2%), physical therapy (55.2%), and medication management (34.5%). Postoperatively, 75% of patients were discharged home, and there were no mortalities within 90 days. There were no significant differences in postoperative outcomes when compared to a contemporary propensity-matched cohort. The remaining seven patients enrolled in POSH did not undergo surgical management after surgery was deemed inconsistent with their goals of care, and three of these patients expired within 1 year of evaluation in POSH.

conclusionsThe POSH model provides high-risk patients with individualized risk stratification, comprehensive interdisciplinary strategies for risk mitigation, and alignment of care with patient goals. When elective colorectal surgery was within their goals of care, frail older adults safely underwent operative intervention after careful perioperative optimization. Future studies should include a mixed-method exploration of the patient perspective and a randomized controlled trial to quantify the impact of the POSH clinic on short- and long-term postoperative outcomes.

Indexed as

Colorectal SurgeryElective Surgical ProceduresFrail ElderlyPerioperative CareAgedAged, 80 and overFemaleGeriatric AssessmentHumansMalePatient Care TeamPostoperative ComplicationsRetrospective Studiescolorectal surgeryfrailtyperioperative optimization

Identifiers

PMID41387097
PMCPMC13173556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.