Evidence map›Paper›PMID 41386957›Full record

ArticleJACC. Case reports2025

Use of a Novel Physician-Modified Frozen Elephant Trunk to Manage an Acute Aortic Arch Aneurysm.

Enrico Rinaldi, Alessandro Castiglioni, Carlotta Bugna, Annarita Santoro, Benedetto Del Forno, Alessandro Verzini, Alessandro Faggi, Andrea Kahlberg, Germano Melissano, Roberto Chiesa

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Enrico RinaldiDivision of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address: rinaldi.enrico@hsr.it.
Alessandro CastiglioniDivision of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Carlotta BugnaDivision of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Annarita SantoroDivision of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Benedetto Del FornoDivision of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Alessandro VerziniDivision of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Alessandro FaggiDivision of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Andrea KahlbergDivision of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Germano MelissanoDivision of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Roberto ChiesaDivision of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe frozen elephant trunk (FET) technique has become a cornerstone in managing complex aortic arch disease. However, commercial FET systems may be unavailable in emergent situations, necessitating alternative solutions. FIRST-IN-HUMAN/EARLY REPORTS SUMMARY: In a 57-year-old man with an acute arch aneurysm with dissection, we replicated the FET configuration by back-table modification of a standard thoracic stent graft and combining it with a surgical graft. This novel approach, the "C-tag Endograft SanRaffaele Arrangement to Re-create a frozen Elephant trunk" (CESARE), provides a rapid, adaptable solution for emergent aortic arch repair with FET when commercial devices are unavailable. DISCUSSION: The modified device was prepared in 65 minutes and was deployed under moderate hypothermic circulatory arrest, with uneventful recovery and excellent early imaging. NOVELTY: CESARE is a rapid, customizable, and widely accessible alternative to FET. TAKE-HOME MESSAGE: This technique enables effective arch repair when standard FET prostheses are unavailable.

Indexed as

aortacardiovascular diseasechest paindissectionstentsthoracictreatmentvascular disease

Identifiers

PMID41386957
PMCPMC12861648

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.