ArticleJACC. Case reports2025
Methamphetamine-Induced Coronary Vasospasm and Recurrent Cardiac Arrest: A Quick Glance May Not Be Good Enough.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundMethamphetamine can cause coronary vasospasm and atherosclerotic plaque disruption, leading to myocardial ischemia and tachyarrhythmias. CASE SUMMARY: A 51-year-old man experienced recurrent episodes of polymorphic ventricular tachycardia (PMVT) and cardiac arrest after using methamphetamine. Initial coronary angiography (CA) revealed diffuse multivessel coronary artery disease; therefore, percutaneous coronary intervention was deferred. On day 12 of hospitalization, he developed acute anterior ST-segment elevation myocardial infarction complicated by PMVT and cardiac arrest. Repeat CA revealed only a single focal culprit lesion in the mid-left anterior descending artery. This was simply treated with a single drug-eluting stent. DISCUSSION: Coronary vasospasm can make detection of culprit lesions on CA alone difficult. Reassessment after administration of vasodilators should be considered. TAKE-HOME MESSAGES: Methamphetamine can induce severe coronary vasospasm, endothelial dysfunction, and atherosclerotic plaque disruption. Vasodilators should be considered during coronary angiography before determining next steps in management.
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