ArticleJACC. Case reports2025
OPTEM-oHCM: OPtimal Targeted Polymer-based EMbolization for Obstructive Hypertrophic CardioMyopathy.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Methodological Considerations on Targeted Polymer Embolization in Obstructive Hypertrophic Cardiomyopathy.JACC. Case reports · 2026Article
- Reply: Methodological Considerations on Targeted Polymer Embolization in Obstructive Hypertrophic Cardiomyopathy.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObstructive hypertrophic cardiomyopathy often requires septal reduction in symptomatic patients, but standard alcohol septal ablation may be limited in some cases. CASE SUMMARY: A 72-year-old woman presented with dyspnea and syncope. Investigations revealed dynamic left ventricular outflow tract gradient up to 167 mm Hg. Targeted embolization using ethylene-vinyl alcohol copolymer on septal and circumflex branches achieved complete gradient resolution. DISCUSSION: This case demonstrates polymer-based embolization as a feasible alternative for complex cases, offering precise targeting beyond traditional septal branches, aligned with current guidelines for nonsurgical candidates. TAKE-HOME MESSAGES: Polymer embolization provides effective left ventricular outflow tract relief in obstructive hypertrophic cardiomyopathy with atypical supply. Functional balloon testing optimizes outcomes in high-risk patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.