Evidence map›Paper›PMID 41386942›Full record

ArticleJACC. Case reports2025

Percutaneous Closure of Residual Shunt After Patent Foramen Ovale Closure With a Biodegradable Occluder.

Dong Luo, Luxi Guan, Hongxiao Li, Jianhua Lv, Haibo Hu, Xiangbin Pan

Abstract read
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dong LuoCenter of Structural Heart Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Luxi GuanCenter of Structural Heart Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Hongxiao LiHebei General Hospital, Hebei, China.
Jianhua LvCenter of Structural Heart Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Haibo HuCenter of Structural Heart Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. Electronic address: hhb.fwhospital@hotmail.com.
Xiangbin PanCenter of Structural Heart Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. Electronic address: panxiangbin@fuwaihospital.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResidual right-to-left shunt (RLS) after patent foramen ovale (PFO) closure may lead to recurrent stroke or migraine. Conventional metallic occluders often entail shortcomings, including suboptimal conformability and permanent metal implantation. Biodegradable occluders offer potential advantages through enhanced compatibility and gradual resorption. CASE SUMMARY: A 52-year-old woman who developed recurrent cerebral infarction and migraine 20 months after PFO closure was diagnosed with a residual RLS, which was subsequently successfully treated using a biodegradable PFO occluder. DISCUSSION: We herein report a successful case of residual RLS management using a biodegradable PFO occluder, offering a novel therapeutic strategy for the treatment of residual shunts after PFO closure. NOVELTY: To our knowledge, this is the first reported case demonstrating the successful clinical application of a biodegradable PFO occluder for the transcatheter closure of residual shunt after initial PFO closure. TAKE-HOME MESSAGE: This case highlights the feasibility and efficacy of a biodegradable device for managing residual shunt, providing a novel therapeutic option in selected patients.

Indexed as

biodegradable occluderpatent foramen ovaleresidual shunttranscatheter closure

Identifiers

PMID41386942
PMCPMC12861682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.