Evidence map›Paper›PMID 41386940›Full record

ArticleJACC. Case reports2025

Tricuspid Valve Endocarditis: A Case of Klebsiella pneumoniae With Pulmonic Embolization.

Nazanin Hazhir Karzar, Abbas Mohammadi, Badi Eghterafi, Dima Youssef

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nazanin Hazhir KarzarDepartment of Internal Medicine, Valley Health System, Las Vegas, Nevada, USA. Electronic address: https://twitter.com/DrBase_AMD.
Abbas MohammadiDepartment of Internal Medicine, Valley Health System, Las Vegas, Nevada, USA. Electronic address: abbas_pr2005@hotmail.com.
Badi EghterafiDepartment of Family Medicine, Valley Hospital Medical Center, Las Vegas, Nevada, USA.
Dima YoussefDepartment of Internal Medicine, Valley Health System, Las Vegas, Nevada, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTricuspid valve endocarditis due to Klebsiella pneumoniae is rare but severe, with metastatic complications. CASE SUMMARY: A 39-year-old woman with a history of substance use disorder (SUD) and previous infective endocarditis (IE) presented with fever, necrotizing pneumonia, and vision loss. Transesophageal echocardiography revealed tricuspid valve vegetation, and blood cultures confirmed Kpneumoniae, meeting Duke-ISCVID criteria for IE. Imaging showed septic pulmonary emboli and splenomegaly; retinal detachment was noted, but its link to the IE remained unclear. The patient improved with 6 weeks of ceftriaxone therapy, although valve repair was avoided given high relapse risk. DISCUSSION: Kpneumoniae endocarditis (1.5% of cases) involves aggressive valvular destruction and embolic events. This case highlights diagnostic challenges (negative transthoracic echocardiography), systemic complications, and management dilemmas in patients with SUD. Uncertain retinal detachment linkage emphasizes shunt evaluation in systemic embolization. TAKE-HOME MESSAGES: Maintain high suspicion for tricuspid endocarditis in SUD patients with septic emboli; transesophageal echocardiography is critical. Multidisciplinary care with prolonged antibiotics and harm-reduction strategies is vital.

Indexed as

intravenous drug useKlebsiella pneumoniaeseptic embolizationtricuspid valve endocarditis

Identifiers

PMID41386940
PMCPMC12861662

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.