Evidence map›Paper›PMID 41386825›Full record

ArticleJournal, genetic engineering & biotechnology2025

Phytochemical screening and inhibitory effects of Catha edulis Forsk extracts on oxidation, growth, biofilm and quorum sensing of selected pathogens.

Yonatan Nesru, Muktar Ahmed, Adam Mengistu, Mohammed Naimuddin

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Article in Journal, genetic engineering & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yonatan NesruDepartment of Applied Biology, School of Applied Natural Sciences (SoANS), Adama Science and Technology University, P. O. Box 1888, Adama, Ethiopia.
Muktar AhmedInstitute of Pharmaceutical Sciences, Adama Science and Technology University, P. O. Box 1888, Adama, Ethiopia.
Adam MengistuDepartment of Biotechnology, Bule Hora University, P.O. Box 144, Bule Hora, Ethiopia.
Mohammed NaimuddinDepartment of Applied Biology, School of Applied Natural Sciences (SoANS), Adama Science and Technology University, P. O. Box 1888, Adama, Ethiopia. Electronic address: mnaimuddin@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of infectious diseases is increasingly challenging due to the emergence and re-emergence of antibiotic-resistant bacteria. Plant-derived natural products are being explored as potential solutions to this global threat. This study investigated the phytochemical composition of Catha edulis and biological properties of its extracts, focusing on their potential as antioxidants and antimicrobials. Gas chromatography/mass spectrometry (GC/MS) of the methanol extract (MeOHE) fractions revealed 11 compounds in dichloromethane fraction (DCMF) and 30 compounds in ethyl acetate fraction (EAF), many of which possess bioactive functions as antioxidants and antimicrobials. Phytol was detected at 60.32 %, not reported before in C. edulis. The antioxidation potential of extracts was assayed by radical scavenging activity (RSA), and the IC

Indexed as

AntimicrobialAntimicrobial resistanceAntioxidantBiofilmCatha edulisQuorum sensing

Identifiers

PMID41386825
PMCPMC12410544

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.