Evidence map›Paper›PMID 41385639›Full record

ArticleScience advances2025

Total synthesis of zwitterionic PS A2 oligosaccharides from

Xinxin Li, Qingzhi Pan-Gao, Yongyong Wan, Fuxing Zeng, Jianying Qi, Yuanhong Tu, Liming Wang, Zhen Wang, Jeroen D C Codée, Qingju Zhang

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In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinxin LiNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.
Qingzhi Pan-GaoNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.
Yongyong WanNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.
Fuxing ZengNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.
Jianying QiNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.
Yuanhong TuNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.
Liming WangNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.ORCID 0009-0009-3460-8560
Zhen WangNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.ORCID 0009-0003-3747-4373
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, Netherlands.ORCID 0000-0003-3531-2138
Qingju ZhangNational Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, 99 Ziyang Avenue, Nan Chang 330022, China.ORCID 0000-0002-6225-4183

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zwitterionic polysaccharides have unique structures and can elicit T cell-dependent immune responses. To unravel their molecular mode of action and develop potential alternatives for carrier proteins in carbohydrate-based vaccines, we here describe a total synthesis of zwitterionic PS A2 oligosaccharides from

Indexed as

Bacteroides fragilisOligosaccharidesPolysaccharides, BacterialGlycosylationStereoisomerismOligosaccharidesPolysaccharides, Bacterial

Identifiers

PMID41385639
PMCPMC12700203

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.