Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Lydia A SibleyCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-6364-7448
Maureen N CowanCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0001-6842-8175
Abigail G KellyCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.
NaaDedee A AmadiCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.
Isaac W BabcockCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0003-0360-0821
Sydney A LabuzanCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-5967-4523
Michael A KovacsCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-4298-9609
Samantha J BatistaCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.
John R LukensCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.
Tajie H HarrisCenter for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-1355-2109
Funding
INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007267 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GARCIA-BLANCO, MARIANO A. · 1985 to 2024
$13.4M
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2M
BIOTECHNOLOGY TRAINING PROGRAMT32GM008715 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LAURIE, GORDON WILLIAM · 2000 to 2019
$6.6M
Alarmin-mediated control of CNS infectionR01NS112516 · NINDS · UNIVERSITY OF VIRGINIA · PI HARRIS, TAJIE H. · 2020 to 2023
$1.9M
Caspase-8 mediated control of CNS infectionR01NS134747 · NINDS · UNIVERSITY OF VIRGINIA · PI TAJIE H. HARRIS · 2024 to 2026
$1.5M
Brain, Immunology and Glia Training ProgramT32NS115657 · NINDS · UNIVERSITY OF VIRGINIA · PI Alban P Gaultier, TAJIE H. HARRIS · 2021 to 2026
$1.2M
The role of meningeal lymphatic vasculature in regulating immunity and intracranial pressure during central nervous system infectionF30AI154740 · NIAID · UNIVERSITY OF VIRGINIA · PI KOVACS, MICHAEL · 2021 to 2021
Cell death is an integral restriction mechanism against intracellular pathogens. We have previously reported extensive cell death in the brain during infection with the intracellular parasite,
Indexed as
BrainCaspase 8CD8-Positive T-LymphocytesToxoplasmaToxoplasmosisAnimalsApoptosisAstrocytesMiceMice, Inbred C57BLMice, KnockoutNeuronsReceptor-Interacting Protein Serine-Threonine KinasesCasp8 protein, mouseCaspase 8Receptor-Interacting Protein Serine-Threonine KinasesRipk3 protein, mouse
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Caspase-8 expression in CD8 · full record | OpenQuestion