In one paragraphArticle in Journal of neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
18 authors.
Matthew A T ElliottDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.
John P AndrewsDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, United States.ORCID 0000-0002-8025-1525 Tjitse van der MolenDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0001-6147-542X Jinghui GengUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0002-3431-9568 Alex SpaethUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0003-0702-3945 Anna ToledoUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, California, United States.
Kateryna VoitiukDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0002-6392-5188 Cordero CoreScientific Software Engineering Center, eScience Institute, University of Washington, Seattle, Washington, United States.ORCID 0000-0002-3531-3221 Thomas GillespieDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.
Ari SinervoUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, California, United States.
David F ParksDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0002-4635-8206 Ash RobbinsUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, California, United States.
Daniel SolísDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0009-0002-3261-7833 Edward F ChangDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, United States.
Tomasz Jan NowakowskiDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, United States.
Mircea TeodorescuUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0001-7085-5248 David HausslerDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.
Tal SharfDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States.ORCID 0000-0002-7899-2818 Funding
Nanoparticle Tracking Analyzer (NTA) for the Center for Live Cell GenomicsRM1HG011543 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, SALAMA, SOFIE REDA · 2021 to 2025
$12.0MIRACDA at UCSC and CSUMBK12GM139185 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI FORSBERG, CAMILLA, HINCK, LINDSAY E · 2020 to 2024
$4.1MDissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.R01MH120295 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SALAMA, SOFIE REDA · 2020 to 2024
$3.7MMachine Learning Augmented Discovery of AAV Capsids for Cell Type Specific Access into Human Neurons and GliaUF1MH130700 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI NOWAKOWSKI, TOMASZ, SCHAFFER, DAVID V · 2022 to 2022
$2.9MDevelopmental Timing During Cortical DevelopmentR01NS123263 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Tomasz Nowakowski · 2022 to 2026
$2.1MUCSC Graduate Program in Genome SciencesT32HG012344 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Angela Norie Brooks, Christopher Vollmers · 2022 to 2026
$1.5MHHS | National Institutes of Health (NIH) K12GM139185HHS | National Institutes of Health (NIH) R01NS123263HHS | National Institutes of Health (NIH) T32HG012344HHS | National Institutes of Health (NIH) UF1MH130700HHS | NIH | National Human Genome Research Institute (NHGRI) 1RM1HG011543HHS | NIH | National Institute of Mental Health (NIMH) R01MH120295HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) 5R25NS070680-13National Science Foundation (NSF) 2034037National Science Foundation (NSF) 2134955NHGRI NIH HHS RM1 HG011543NHGRI NIH HHS T32 HG012344NIMH NIH HHS UF1 MH130700NINDS NIH HHS R01 NS123263Schmidt Futures (Schmidt Futures Projects, LLC) SF 857
6 · The paper itselfAbstract
Neuronal firing patterning in the dentate gyrus of patients with epilepsy remains unknown at the microcircuit level. Advancements in high-density CMOS-based microelectrode arrays can be harnessed to study network activity with unprecedented spatial and temporal resolution. We use novel computational methods with high-density electrophysiology recordings to spatially map network activity of human hippocampal brain slices from six patients with mesial temporal lobe epilepsy. Two slices from the dentate gyrus exhibited synchronous bursting activity in the presence of low magnesium media with kainic acid, representative of seizure-like behavior. We bridged microscale circuit dynamics with alterations in theta oscillations at the network scale. Future studies may apply this approach to spatially elucidate functional networks and their possible role in seizures.
Indexed as
Action PotentialsBrain MappingDentate GyrusEpilepsy, Temporal LobeHippocampusNeuronsAdultFemaleHumansMaleMiddle AgedTheta Rhythmcomputational neuroscienceepilepsyfunctional neuroscienceneural dynamicsneurosurgery
Identifiers
PMID41385612
PMCPMC12931417
What OpenQuestion holds
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