Article in Science immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
24 authors.
Thomas M FentonMucosal Immunology Group, Department of Health Technology, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark.ORCID 0000-0002-6200-6403
Line WulffMucosal Immunology Group, Department of Health Technology, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark.ORCID 0000-0002-7482-4569
Venla VäänänenLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-6366-1610
Gareth-Rhys JonesSchool of Infection and Immunity, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK.
Camilla Koldbæk LemvighLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-5772-8743
Lene B RiisDepartment of Pathology, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.ORCID 0000-0003-4669-3159
Mads Damsgaard WewerGastro Unit, Medical Section, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0001-9140-9706
Julien VandammeMucosal Immunology Group, Department of Health Technology, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark.
Peter B JørgensenMucosal Immunology Group, Department of Health Technology, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark.ORCID 0000-0001-5262-0074
Calum C BainSchool of Infection and Immunity, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0001-8884-327X
Kirstine G BellingDepartment of Public Health, University of Copenhagen and Novo Nordisk Foundation Center for Protein Research University of Copenhagen, 2200 Copenhagen N, Denmark.ORCID 0000-0001-5664-1948
Gwo-Tzer HoSchool of Infection and Immunity, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0002-6014-372X
Tune H PersTranslational Disease Systems Biology, Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-0207-4831
Anja PoulsenDepartment of Digestive Diseases, Transplantation and General Surgery, Section for IBD, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-0314-3467
Gorm R MadsenGastro Unit, Medical Section, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0001-5525-7338
Ole H NielsenDepartment of Gastroenterology, Medical Section, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark.ORCID 0000-0003-4612-8635
Henrik L JakobsenDepartment of Surgery, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.ORCID 0000-0001-5611-6692
Jose Mg IzarzugazaCenter for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark.ORCID 0000-0003-1754-5122
Flemming BendtsenGastro Unit, Medical Section, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Denmark.ORCID 0000-0002-8419-2104
Søren BrunakDepartment of Public Health, University of Copenhagen and Novo Nordisk Foundation Center for Protein Research University of Copenhagen, 2200 Copenhagen N, Denmark.ORCID 0000-0003-0316-5866
Allan M MowatSchool of Infection and Immunity, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0001-9389-3079
Lars R OlsenLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-6725-7850
Urs MörbeLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0001-8747-437X
William W AgaceMucosal Immunology Group, Department of Health Technology, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark.ORCID 0000-0003-3823-5772
Funding
Wellcome Trust
6 · The paper itself
Abstract
Understanding of mononuclear phagocyte (MNP) diversity in the human intestine and the alterations this compartment undergoes in inflammation remains incomplete. Here, we used single-cell RNA sequencing, cellular indexing of trancriptomes and epitopes by sequencing, flow cytometry, and imaging to explore MNP heterogeneity in human ileal and colonic laminae propriae (LPs) in health and Crohn's disease (CD). In addition to monocytes, macrophage subsets, and conventional type 1 dendritic cells (cDC1s) and cDC2s, we found a CD1c
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease. · full record | OpenQuestion