Evidence map›Paper›PMID 41385546›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Glomerular endothelial cells eliminate nicotinamide adenine dinucleotide to instruct CD103

Li Jia, Mengdi Liu, Huiyan Ji, Jiaxin Lei, Danhua Su, Lingyi Li, Ting Liu, Fenghong Yuan, Lin Xu, Qinghua Cao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Li Jia *The Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.
Mengdi Liu *The Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.
Huiyan Ji *The Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.
Jiaxin LeiThe Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.
Danhua SuThe Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.
Lingyi LiThe Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.
Ting LiuDepartment of Rheumatology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi 214000, Jiangsu Province, China.
Fenghong YuanDepartment of Rheumatology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi 214000, Jiangsu Province, China.
Lin XuDepartment of Immunology, Zunyi Medical University, Zunyi 563000, Guizhou Province, China.
Qinghua CaoRenal Medicine, Faculty of Medicine and Health, Kolling Institute of Medical Research, Sydney Medical School, University of Sydney, St Leonards, NSW 2065, Australia.
Huimin ZhangDepartment of Molecular Cell and Systems Biology, University of California, Riverside, CA 92521.ORCID 0000-0003-1143-9388
Zhenke WenThe Fourth Affiliated Hospital of Soochow University, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Soochow University, Suzhou 215123, Jiangsu Province, China.ORCID 0000-0003-0542-0349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lupus nephritis (LN), which is characterized by the accumulation of DNA-containing immune complexes (ICs), is the leading cause of death in patients with systemic lupus erythematosus (SLE). While growing evidence highlights the central role of CD103

Indexed as

Antigens, CDCD4-Positive T-LymphocytesEndothelial CellsIntegrin alpha ChainsKidney GlomerulusLupus NephritisADP-ribosyl Cyclase 1AnimalsCell DifferentiationFemaleHumansLupus Erythematosus, SystemicMicePositive Regulatory Domain I-Binding Factor 1Signal TransductionADP-ribosyl Cyclase 1alpha E integrinsAntigens, CDIntegrin alpha ChainsPositive Regulatory Domain I-Binding Factor 1CD103+ T cellendothelial cellLupus nephritis

Identifiers

PMID41385546
PMCPMC12718392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.