Evidence map›Paper›PMID 41385527›Full record

ArticlePloS one2025

Coping with rejection as a sperm donor: A qualitative study of the personal impact of rejection and new health information.

Lina Thirup, Anne-Bine Skytte, Ulrik Schiøler Kesmodel, Ida Vogel, Guido Pennings, Allan Pacey, Stina Lou

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lina ThirupCryos International, Aarhus, Denmark.ORCID https://orcid.org/0009-0006-1945-3335
Anne-Bine SkytteCryos International, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-0067-9557
Ulrik Schiøler KesmodelCryos International, Aarhus, Denmark.
Ida VogelCenter for Fetal Diagnostics, Aarhus University, Aarhus, Denmark.
Guido PenningsDepartment of Philosophy and Moral Science, Bioethics Institute Ghent (BIG), Universiteit Gent, Gent, Belgium.
Allan PaceyFaculty of Biology, Medicine and Health, School of Medical Sciences, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0002-4387-8871
Stina LouCenter for Fetal Diagnostics, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0001-6177-5780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe demand for sperm donation is increasing, yet only a small percentage of applicants are accepted, and little attention has been given to those who are rejected. The application process may reveal new medical or genetic information with potential personal and emotional consequences. The aim of this study was to explore how men experience rejection as sperm donors, including how they cope with the rejection and integrate potential new information into their lives.

methodsWe conducted qualitative, in-depth interviews with 19 men rejected as sperm donors. Data was analyzed using thematic analysis.

resultsSome men received new medical information that raised significant concerns, particularly regarding their health, fertility, and family. However, for most it was not the reason for rejection that affected them most, but the rejection itself. They had begun to identify as donors, and being turned down felt like a blow to their sense of self. Over time, participants used different coping strategies: information seeking, actionable reasoning, positive reframing, normalizing, and postponing. Although the experience was personally and emotionally challenging for many, it ultimately did not have a lasting negative impact on their lives.

conclusionsSperm donation is not only a medical act but also tied to social identity, with rejection having personal and emotional consequences. For men whose rejection is based on new medical information that causes significant concerns, sperm banks should support rejected donors and help them exit the process positively. Further research is warranted to find out how this can be done.

Indexed as

Adaptation, PsychologicalSpermatozoaTissue DonorsAdultHumansMaleMiddle AgedQualitative ResearchYoung Adult

Identifiers

PMID41385527
PMCPMC12700407

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.