Observational studyIndian journal of ophthalmology2026
Intravitreal triamcinolone acetonide therapy in serpiginous-like choroiditis.
Observational study in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Critical appraisal of intravitreal triamcinolone acetonide for serpiginous-like choroiditis in a tuberculosis-endemic setting.Indian journal of ophthalmology · 2026Article
- Response to comments on "Intravitreal triamcinolone acetonide therapy in serpiginous-like choroiditis".Indian journal of ophthalmology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
purposeTo evaluate the efficacy and safety of 2 mg intravitreal triamcinolone acetonide (IVTA) in the management of serpiginous-like choroiditis (SLC), and study lesion resolution, recurrence, paradoxical worsening, and systemic medication burden.
methodsThis retrospective observational study included patients with SLC receiving 2 mg IVTA with a minimum follow-up of 6 months. Demographic data, clinical findings, imaging, and treatment details were retrieved from medical records. The primary outcomes were time to lesion resolution, incidence of paradoxical worsening, recurrence rate, and the need for repeat IVTA. Secondary outcomes were changes in best-corrected visual acuity (BCVA) and intraocular pressure (IOP). Use of systemic corticosteroids was also recorded.
resultsFifteen eyes of 14 patients were analyzed. The mean age was 31.5 years, and 71.4% were managed without systemic corticosteroids. All patients received IVTA; 11 received concurrent anti-tubercular therapy (ATT). Mantoux positivity was observed in 64.2%, QuantiFERON-TB Gold in 78.5%, and both were positive in 57.1% of patients. Mean clinical and fundus autofluorescence (FAF)-based lesion resolution time was 2.7 and 5.9 months, respectively. No cases of paradoxical worsening were noted. Recurrence occurred in three eyes, two of which did not receive ATT. Mean BCVA improved from 20/50 to 20/32 ( P = 0.006). IOP elevation >21 mm Hg occurred in 33.3% of eyes and was controlled with topical medications. Cataract developed in 38.4% of eyes, and one eye required surgery. The mean follow-up was 18.2 months.
conclusionIVTA at a 2 mg dose appears effective in lesion resolution, while minimizing systemic therapy in SLC, with an acceptable safety profile and no paradoxical worsening. Larger prospective studies are needed to validate these findings.
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